Our breakthrough technology combines synthetic and stem cell biology, offering limitless possibilities. Enabling a new generation of cell therapies, providing the best human cells for research and drug discovery, and allowing the control of advanced synthetic biology circuits for biomanufacturing.
Application: precise reprogramming of stem cells
Reprogramming stem cells into functional skeletal muscle
(8-day timecourse; final contraction assay by addition of acetyl choline)
Batch to batch reproducibility for applications including high throughput screening and cell therapy
Unprecedented purity results compared to current technologies.
Industrial-scale quantities and order-of-magnitude lower costs
Production takes days not months results in significant associated benefits
Current cell product offerings
Human-Induced
Skeletal
Myocytes
Human-Induced
Glutamatergic
Cortical Neurons
Our team
Biology turns engineering
As we reach the “read/write” stage of biology, evolution is proving to be the ultimate algorithm, allowing us to increasingly program biological systems. A foundational shift in biology from being an empirical science towards becoming an engineered discipline is underway.
Ramy Ibrahim
PhD, SAB Member
Ramy is a leading immuno-oncology clinician who has helped to develop some of the breakthrough therapies in this field. Ramy has served as the Vice President of Clinical Development for Immuno-oncology at AstraZeneca, and as a member of the Bristol-Myers Squibb Immuno-oncology program. Ramy is currently the Chief Medical Officer at the Parker Institute of Cancer Immunotherapy.
Mark Kotter
MD, PhD, Founder/CEO
Mark is a stem cell biologist and neurosurgeon at the University of Cambridge. By combining synthetic and stem cell biology, his team has developed a benchmark technology for the efficient and consistent production of human cells for use in research, drug development, and cell therapy. He is the founder of bit bio and co-founder of the cultured meat startup Meatable.
Paul Morrill
PhD, Chief Business Officer
Paul is a serial entrepreneur and scientist with over thirty years of experience in the biotech and pharma sectors. Most recently, he was the commercial founder and President of Horizon Discovery Group, and founder of CellRx Limited, a growth factors company serving the biopharmaceutical sector. Paul holds a PhD in Biotechnology from the University of Cambridge.
Roger Pedersen
PhD, Chief Scientific Advisor
Roger is a pioneer researcher and thought leader in stem cell biology. He discovered the culture conditions for maintaining human pluripotency and inducing differentiation to key body tissues, and he developed one of the first reprogramming protocols. In addition, Roger was founder of the Cambridge Stem Cell Institute. His lab is focused on the differentiation of human pluripotent stem cells, with potential applications for drug discovery, toxicity testing and cell therapies.
Florian Schuster
CFO / COO
Florian is an active entrepreneur and investor. He is the co-founder of bit bio. Previously, he was CFO & Head of Strategic Partnerships for Tessa Therapeutics, a clinical-stage cell therapy company. Florian is a former investment banker, a graduate of the Stanford School of Engineering, and an alumnus of Harvard Business School.
Marius Wernig
PhD, SAB Member
Marius’ seminal 2010 paper in Nature demonstrating direct conversion of fibroblasts into neurons has sparked a widespread interest in cell reprogramming. He is the co-director of the Stanford Stem Cell Institute. His lab uses cellular reprogramming to understand how neurons are induced, and how they mature and maintain their identity.
News
Introducing bit bio — coding cells, the building blocks of life.
Learn more about the potential of #cellularreprogramming from bit bio founder #MarkKotter.
Published on medium.com
Elpis becomes bit bio. We are excited to announce our transition to the cell coding company!
Who we are : Founded in 2016 by Dr Mark Kotter, bit bio (formerly Elpis Biomed) is an award-winning spinout from the University of Cambridge. By...
Mastering the art of reprogramming human cells
The development of the Cambridge Biomedical Campus now speaks of a world-class scientific healthcare hub – and its newest arrival is Elpis BioMed, who have moved in to the Abcam building.
Cambridge Start-Up of the Year
Elpis Wins 2018 Cambridge Independent Start-Up of the Year Award Elpis was voted as the 2018 Cambridge Start-Up of the Year among a highly...
Elpis human cell models could potentially replace animal experiments in drug discovery
Dr Jonathan Milner mentioned Elpis during his plenary lecture at the 2018 European Laboratory Research & Innovation Group (ELRIG) Drug Discovery...
Physiologically relevant cell models in neurology
Join us for a webinar with a panel of experts: Andrew Bassett PhD, Head of Research at the Wellcome Trust Sanger Institute Mark Kotter,...
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