Our breakthrough technology combines synthetic and stem cell biology, offering limitless possibilities. Enabling a new generation of cell therapies, providing the best human cells for research and drug discovery, and allowing the control of advanced synthetic biology circuits for biomanufacturing.
Read more: Introducing bit.bio — coding cells, the building blocks of life
Application: precise reprogramming of stem cells
Reprogramming stem cells into functional skeletal muscle
(9-day time course; final contraction assay by addition of acetylcholine)
Cell products
Human-Induced
Glutamatergic
Neurons
Human-Induced
Skeletal
Myocytes
Batch to batch reproducibility for applications including high throughput screening and cell therapy
Unprecedented purity results compared to current technologies.
Industrial-scale quantities and order-of-magnitude lower costs
Production takes days not months results in significant associated benefits
Our team
Biology turns engineering
As we reach the “read/write” stage of biology, evolution is proving to be the ultimate algorithm, allowing us to increasingly program biological systems. A foundational shift in biology from being an empirical science towards becoming an engineered discipline is underway.
Ramy Ibrahim
MD, SAB Member
Ramy is a leading immuno-oncology clinician who has helped to develop some of the breakthrough therapies in this field. Ramy has served as the Vice President of Clinical Development for Immuno-oncology at AstraZeneca, and as a member of the Bristol-Myers Squibb Immuno-oncology program. Ramy is currently the Chief Medical Officer at the Parker Institute of Cancer Immunotherapy.
Mark Kotter
MD, PhD, Founder/CEO
Mark is a stem cell biologist and neurosurgeon at the University of Cambridge. By combining synthetic and stem cell biology, his team has developed a benchmark technology for the efficient and consistent production of human cells for use in research, drug development, and cell therapy. He is the founder of bit.bio and co-founder of the cultured meat startup Meatable.
Paul Morrill
PhD, Chief Business Officer
Paul is a serial entrepreneur and scientist with over thirty years of experience in the biotech and pharma sectors. Most recently, he was the commercial founder and President of Horizon Discovery Group, and founder of CellRx Limited, a growth factors company serving the biopharmaceutical sector. Paul holds a PhD in Biotechnology from the University of Cambridge.
Roger Pedersen
PhD, Chief Scientific Advisor
Roger is a pioneer and thought leader in the field of human stem cell biology. His lab was the first to isolate pluripotent epiblast stem cells from the epiblast layer of the developing mammalian embryo. In addition, he developed one of the first cellular reprogramming protocols. Roger was co-founder of the Cambridge Stem Cell Institute. His lab is currently focused on differentiation of pluripotent stem cells, with potential applications for drug discovery, toxicity testing and cell therapies.
Florian Schuster
CFO / COO
Florian is an active entrepreneur and investor. He is the co-founder of bit.bio. Previously, he was CFO & Head of Strategic Partnerships for Tessa Therapeutics, a clinical-stage cell therapy company. Florian is a former investment banker, a graduate of the Stanford School of Engineering, and an alumnus of Harvard Business School.
Marius Wernig
PhD, SAB Member
Marius’ seminal 2010 paper in Nature demonstrating direct conversion of fibroblasts into neurons has sparked a widespread interest in cell reprogramming. He is the co-director of the Stanford Stem Cell Institute. His lab uses cellular reprogramming to understand how neurons are induced, and how they mature and maintain their identity.
News
Can We Recreate Every Human Cell Type In The Body? This UK Startup Thinks So
Published on Forbes.
Bit Bio, a UK synthetic biology startup backed by Silicon Valley investors, has partnered with the London Institute for Mathematical Sciences, marking a milestone in the fusion of biology and mathematics for coding human cells.
Bit.Bio: British firm cracks code for stem cells
Published on The Times.
Now a British company, Bit.Bio, has received £40m of backing for technology that it claims can reliably reprogram stem cells, producing a cellular vending machine to make any human cell you desire.
bit.bio joins forces with maths institute to find the ‘operating system of life’
Cell coding startup and science institute partner on a moonshot mission to create every human cell type for biomedical research and therapy
Bit Bio’s ‘enter button for the keyboard to the software of life’ nabs the company $41.5 million
Published on TechCrunch.
Bit Bio, the new startup that pitches itself as the “enter button for the keyboard to the software of life,” only needed three weeks to raise its latest $41.5 million round of funding.
Sure, Bit Bio got some significant cash for its cell coding work. But it’s the insiders who are backing them that will garner the attention
Published on Endpoints News.
Mark Kotter’s synthetic biology team at Bit Bio has already won lots of local recognition in the UK for its tech for precision reprogramming of stem cells at an industrial scale. Now they have a jolt of cash from some marquee US investors to fuel the work and drive some added global panache for the biotech’s profile.
‘Beautiful science’ in ‘operating system of life’ underpins $41.5m investment in Bit Bio
Published on Cambridge Independent.
Discovery Drive-based synthetic biology specialist Bit Bio has closed a $41.5million Series A investment, bringing the company’s total funding to $50million.
Bit Bio secures $41.5 million of funding from top life sciences investors
Rick Klausner, Bob Nelsen, and Jim Tananbaum team up with Bit Bio to uncover the “operating system of life” and accelerate the company’s drive...
Advances in cellular reprogramming: from stem cells to printed tissues
Webinar - on demand Speakers: Prof Hagan Bayley & Dr Mark Kotter Monday June 29 4pm GMT | 8am PST | 11am EST 60 minutes Listen to our...
ISSCR Annual Meeting 2020
Join us at ISSCR 2020 where we will be exhibiting!
Bit Bio Secures Distribution Agreement with Abcam to Democratize Access to Human Cells for Global Life Science Research
Published on PR Newswire.
Bit Bio announces agreement with Abcam, a global innovator in life science reagents and tools, to make bit.bio’s iPSC derived functional human cells widely available to the global life science community.
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