Join the bit.bio team

Cambridge Start Up of the Year 2018

bit.bio is an award-winning spinout from the University of Cambridge. Our breakthrough technology combines synthetic and stem cell biology for the precise, efficient and consistent reprogramming of human cells used in research, drug discovery, and cell therapy. At bit.bio, we are passionate about engineering human cells that will enable the medicine of the future. To do this we need talented and curious people who want to make an impact on the future of science and therapeutics.

As a team of individuals, we value science, collaboration, openness, curiosity and creativity. We are united by trust and respect for each other.

bit.bio provides a vibrant and dynamic work environment in an exciting, fast-moving time for biology. We work with cutting edge technologies and with our world-leading scientific advisory board. We conduct pioneering work with real-world impact.

We trust our people to make significant contributions early on with opportunities to be involved in projects that are key to the success and growth of our young company. We invest in people, creating opportunities for personal development in an inclusive multi-skilled team with ambitious goals that provide opportunities to learn on the job from each other.

Creativity and open minds are encouraged for everyone to contribute to the success of the company.

To support bit.bio staff and our culture further, we also offer a competitive salary, highly competitive benefits package including pension contribution scheme as well as health and life insurance.

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company, please send your CV and cover letter to careers@bit.bio

 

Health and Safety Officer

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Cambridge Based Position

 

Your role in our team:

We are looking for a Health & Safety Officer with a strong background working in a Biotechnology environment, either Industry or Academic, to support our efforts in developing and maintaining a positive health and safety culture. Reporting to our Senior Health and Safety Advisor, the candidate will work in a newly formed and developing Health & Safety team, providing support in creating a safe working environment for both our research and business operations. The candidate will also support the development and implementation of a H&S Management System in line with HSG65 / ISO45001.

 

Your key responsibilities will include:

  • Promoting and maintaining a positive safe working culture.
  • Assist in developing and reviewing H&S policies, safe systems of work and risk assessments.
  • Provide guidance and support to members of the science and manufacturing teams in developing risk assessments specific to work processes.
  • Ensuring that Safe Systems of work, risk assessments and H&S policies are being followed.
  • Developing and delivering safety training modules.
  • Collating near-miss and accident reports, providing support in accident investigation.
  • Being a member of the general health & safety committee.

You…

  • Have an ability to work flexibly and adjust to changing situations and circumstances.
  • Are proactive with a willingness to learn.
  • Have good communication and influencing skills.
  • Have an interest in scientific and technology advancement.
  • Have a Bachelors’ degree in Science or equivalent experience.

Essential for the role:

  • Working in a health and safety role preferably within a biotechnology environment.
  • Health & Safety inspections and audits.
  • Accident reporting and investigations.
  • Cell biology knowledge or experience.

… and possibly…

  • Experience of working at the bench in a scientific research environment, together with working with specialist scientific equipment.
  • Involvement in developing safety training modules and delivering training.
  • NEBOSH National Certificate in Occupational Health & Safety.
  • TECH IOSH membership.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Sales Administrator

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Cambridge Based Position

 

Your role in our team:

We are seeking a meticulous and adaptable Sales Administrator who will have responsibility of providing support to the Commercial group. As part of the role you will deal with customer requests, provide quotations, and information such as stock availability, delivery dates, and manage our purchase orders and invoices.

To ensure success you will ideally have experience in a sales environment, advanced administration skills and an understanding of sales performance metrics and provide administrative support to ensure sales targets are achieved. It is essential that you have a high degree of proficiency in the use of Sales Force CRM to aid in your duties.

 

Your key responsibilities will include:

  • Receiving and processing purchase orders.
  • Issuing sales transaction invoices.
  • Verifying orders, including customer information and payment details.
  • Contacting customers by phone or email to answer any queries and obtain missing information.
  • Maintaining and updating sales and customer records.
  • Compiling monthly sales reports.
  • Expediting orders through internal liaison.
  • Directing feedback from customers to relevant departments.
  • Supporting the commercial department with other administrative tasks as required.

You…

  • Pay meticulous attention to detail.
  • Are adaptable to the changing demands of the Commercial group.
  • Have exceptional interpersonal and customer services skills.
  • Have excellent verbal and written communication skills.
  • Enjoy the fun side of work but are adept at working in a high-performance team culture.
  • Are loyal, motivated and driven, with the desire to build a career.

Essential for the role:

  • A Level or equivalent BTEC education.
  • Previous experience in sales administration or a similar role.
  • Previous experience in a similar capacity in Life Science or within a Products based company.
  • Experience with Sales Force sales management system.
  • Advanced knowledge of administrative record keeping.
  • Familiarity with sales reporting.
  • Monitoring potential opportunities through a tender portal such as Scientist.com or equivalent.

… and possibly…

  • An Associate or Bachelors’ degree in Business Administration or similar.
  • A science background or at least comfortable working in the Life Sciences sector.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Inside Sales Specialist

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Cambridge/Home Office Based Position

 

Your role in our team:

We are looking for an Inside Sales Specialist to join our growing Commercial team. This role will focus on the direct selling of bit.bio’s iPSC-derived cell products to academic and industry sectors and will report into bit.bio’s Head of Inside Sales. The position will be essentially home office based within the assigned territory, although the role will require regular interaction with the Cambridge offices of bit.bio.

 

Your key responsibilities will include:

  • Prospects and sells iPSC-derived cell products in the territory.
  • Owns the complete sales process for the cell products in the territory.
  • Interacts with existing and new customers and converts sales leads into sales.
  • Through consultative selling, matches customer needs to product offerings.
  • Interacts with the marketing department, feeding back the voice of the customer to the relevant marketing personnel.
  • Makes outbound calls to existing and new customers.
  • Documents customer contact information into the CRM database.

You…

  • Are professional and consultative, with the ability to secure business for bit.bio through proactive sales activities directed at decision makers and decision influencers.
  • Are a critical thinker with the ability to be creative.
  • Are self-motivated and driven to achieve sales goals.
  • Are able to assess client needs and craft recommendations through effective written and oral communications.
  • Will interact in a positive way through building trust with technical and marketing teams at bit.bio.

Essential for the role:

  • Science degree or equivalent experience.
  • At least 3 years’ technical experience in a pharmaceutical or biotech company.
  • At least 2 years’ proven sales experience.
  • Demonstrable understanding of the drug development process.
  • Able to interact and listen with customers in a consultative manner to match their requirements with the cell product offering.
  • Ability to work well with highly educated research scientist customers.
  • Good level of proficiency with MS Office.
  • Experience of working with a Sales Force database or equivalent CRM.

… and possibly…

  • Advanced degree – MSc or PhD.
  • Solid technical scientific background coupled with sales experience.
  • Good understanding of the common techniques and methods used in the field of molecular and cell biology.
  • Analytical skills with the ability to analyse and interpret data and produce reports and documents to support sales.
  • Ability to identify leads, assess the value of new business/product opportunities and close deals.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Automation Scientist – Cellular Engineering (Gene Editing and Technology Development)

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for an Automation Scientist with experience in molecular biology and mammalian tissue culture, to plan, perform and evaluate genome engineering experiments in Human iPSCs and mammalian cells. The role has two major focusses; supporting the cell engineering platform, provide provision of a robust, state of the art, in-house service, and to assist in the training and development of Cell Engineering staff. Working closely with the Gene Editing Technological Development team support the development of existing and novel gene editing techniques/platforms as pertains to the team Gene Engineering Technology Development Team and company-wide Objectives and Key Results (OKRs). Reporting to the Senior Scientist- Cellular Engineering Lead, candidates will work with a team of scientists being a focal point within the wider R&D department.

 

Your key responsibilities will include:

  • Utilise existing automation, adapt or integrate new systems to aid in developing state-of-the-art automated cellular engineering, cell culture and molecular biology protocols to increase throughput, reliability and robustness of multiple processes and work-flows.
  • In collaboration with wet-lab scientists actively seek opportunities to interpret manual liquid handling and complex molecular biology and cellular processing SOPs into automated SOPs and workflows. Lead the team in the execution of these workflows.
  • Recommend unexplored and emerging areas for building capabilities and driving innovation.
  • Developing quality assurance and process management documentation to assess delivery against requirements.
  • Train equipment users on key concepts associated with the platforms support best-practice and mitigate avoidable run failures, ensuring optimal routine operation.
  • Establish & maintain strong relationships with vendors and application specialists.

You…

  • Are a good team player with the ability to prioritise, organise and be responsible for your own workload and that of others.
  • Have a track record of optimising SOPs/protocols including the experimental design and empirical assessment and troubleshooting of current SOPs and protocols.
  • Have a proven track record of project delivery.
  • Have a thirst for knowledge.
  • Have the ability to independently drive projects and actively contribute to the projects of colleagues.

Essential for the role:

  • Higher degree in Biological Sciences or equivalent experience.
  • >2 years of experience in operating liquid handling automation.
  • Experience of developing and critically assessing liquid handling platforms to meet desired requirements and specifications.
  • Experience in project management and process development.
  • Proven ability to communicate research/project outputs, through written or oral communication.
  • Excellent team working and networking skills, proven ability to influence on Scientific and non-scientific matters.
  • The ability to effectively communicate with collaborators and occasionally present to large groups.
  • Experienced in mammalian tissue culture.

… and possibly…

  • Ability to use sequence manipulation software (such as Seq. Builder, Snapgene).
  • Practical experience of cellular phenotyping through the use of techniques such as FACS, IHC or other.
  • Strong knowledge of standard Molecular or Cell biology techniques including sample processing.
  • Strong practical and theoretical background in gene editing in ESC, HiPSCs and mammalian cells – experiment quality control and project delivery (>2 years of experience).
  • Experience of C#, Java and other advanced programming languages.
  • Experience and understanding of introducing novel workflows/processes and development of platforms for reagent delivery.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Senior Scientist – Synthetic Biology and Vector Construction (Gene Editing and Technology Development)

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for a Senior Scientist with strong experience in molecular and synthetic biology to join our Technology Development Team. The role is focused on developing and managing a programme of research to develop or implement either existing synthetic biology technology or create novel advancements in cellular programming as pertains to the Gene Engineering Technology Development Team and company-wide Objectives and Key Results (OKRs). Reporting to the Head of Department, Gene Engineering and Technology Development team, candidates will work with a team of scientists being a focal point within the wider R&D department.

 

Your key responsibilities will include:

  • Design, develop and manage the implementation of a programme of research to ensure the company is at the forefront of cellular programming.
  • In concert with the Technology Development team, incorporate novel molecular engineering and gene engineering technologies, processes and applications, some of which will include development of high throughput and automated approaches.
  • Working closely with the Scientific teams, full accountability for developing customised and creative solutions to achieve the companies’ scientific goals, using the latest molecular and synthetic biology technologies.
  • Engage and influence external collaborators (and suppliers). Be involved in initiating, developing and driving collaborations which are critical to the achievement of the team and company Objectives and Key Results (OKRs).
  • Be aware of and regularly scan the horizon of the current I.P. landscape and business development requirements of the company.
  • May include full line management responsibility for all direct reports, motivating and developing them to achieve high levels of performance and productivity. Oversee development and training activities and coach individuals to perform their roles effectively.
  • Actively lead in developing and maintaining the core cultural aspects of the company and deputise for the Head of Department when required.

You…

  • Are a good team player with the ability to prioritise, organise and be responsible for your own workload and that of others.
  • Have a track record of optimising SOPs/protocols including the experimental design and empirical assessment and troubleshooting of current SOPs and protocols.
  • Have a proven track record of project delivery to tight timelines.
  • Have a thirst for knowledge.
  • Have the ability to independently drive your own research and actively contribute to the projects of colleagues.
  • Enjoy tackling research challenges through critical thinking, scientific rigour and inventiveness.

Essential for the role:

  • A PhD in a relevant area of Biological Sciences or equivalent experience and a passion for problem solving.
  • Track record and proven ability to manage multi-disciplinary work tasks and prioritise workload of team.
  • Proven independent working style, technical problem solving, data analysis and generation of novel ideas.
  • Proven experience and track record in using molecular biology to provide creative solutions to biological questions or technical problems.
  • Experience in synthetic biology and cloning. In particular, but not limited to, approaches in the design, construction and multimodal delivery of DNA assemblies into genomes.
  • Demonstrable commitment to developing managerial skills and a track record of training and development.
  • The ability to effectively communicate with collaborators and present to large groups.

… and possibly…

  • Experience in yeast or E. coli synthetic biology.
  • Experience in mammalian cell culture.
  • Experience in genome editing and cellular engineering.
  • Practical experience and knowledge of cellular assays and cell phenotyping (FACS, IHC, clonogenic, cytotoxicity and viability).

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Scientist – Cellular Engineering (Gene Editing and Technology Development)

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for a Scientist with experience in molecular biology, mammalian tissue culture and cellular engineering, to plan, perform and evaluate genome engineering experiments in Human iPSCs and mammalian cells. The role has two major focusses; supporting the cell engineering platform, provide provision of a robust, state of the art, in-house service, and to assist in the training and development of Cell Engineering staff. Working closely with the Gene Editing Technological Development team support the development of existing and novel gene editing techniques/platforms as pertains to the team Gene Engineering Technology Development Team and company-wide Objectives and Key Results (OKRs). Reporting to the Senior Scientist- Cellular Engineering Lead, candidates will work with a team of scientists being a focal point within the wider R&D department.

 

Your key responsibilities will include:

  • Support the design, development and implementation of a state-of-the-art cellular engineering platform. This includes assay design, implementation and execution.
  • LIMS/sample tracking, resource management, SOP and process development.
  • In concert with the Gene Engineering Technology Development team (GETD), incorporate novel cellular engineering and gene editing technologies, processes and applications.
  • Accountable for cell line and reagent delivery to a wide variety of stake holders; internal scientific, manufacturing and external academic and contract research organisations.
  • Engage and influence external collaborators (and suppliers). Be involved in initiating, developing and driving collaborations which are critical to the achievement of the team and company Objectives and Key Results (OKRs).
  • Influence and impact across the wider scientific and manufacturing teams as pertains to gene engineering and cell line development and may sit on a number of key committees.
  • Oversee development and training activities; coach individuals to perform their roles effectively.
  • Actively lead in developing and maintaining the core cultural aspects of the company.

You…

  • Are a good team player with the ability to prioritise, organise and be responsible for your own workload and that of others.
  • Have a track record of optimising SOPs/protocols including the experimental design and empirical assessment and troubleshooting of current SOPs and protocols.
  • Have a proven track record of project delivery.
  • Have a thirst for knowledge.
  • Have the ability to independently drive your own research and actively contribute to the projects of colleagues.

Essential for the role:

  • A PhD in a relevant area of Biological Sciences or equivalent experience and a passion for problem solving.
  • Strong practical and theoretical background in ESC or HiPSC culture.
  • Strong practical and theoretical background in editing ESC, HiPSCs and mammalian cells – experimental quality control and project delivery (>2 years of experience).
  • Ability to manage and prioritise own workload.
  • Experience of coaching, training and development.
  • Well-rounded practical experience and knowledge of cellular assays and cell phenotyping (FACS, IHC, clonogenic, cytotoxicity and viability).
  • The ability to effectively communicate with collaborators and occasionally present to large groups.

… and possibly…

  • Experience in the use and incorporation of automated workflows.
  • Experience in working with IT and informatics teams to develop sample and experiment tracking software/systems.
  • Well-rounded and practical experience in molecular assays and molecular biology (qRT-PCR, scRNA seq, ddPCR, cloning).
  • Good knowledge and experience of performing modern genetic screens.
  • Experience and understanding of introducing novel workflows/processes and development of platforms for reagent delivery.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Research Assistants – Cellular Engineering (Gene Editing and Technology Development)

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for Research Assistants with experience in molecular biology and mammalian tissue culture to plan, perform and evaluate genome engineering experiments in Human iPSCs and mammalian cells. Focused on supporting the cell engineering platform, provide provision of a robust, state of the art, in-house service. This includes platform development, project design, execution and delivery. You will also play a key role in the implementation of new technologies and SOPs as pertains to the Gene Engineering Technology Development Team (GETD) and company-wide Objectives and Key Results (OKRs). Reporting to a senior member of the Cellular Engineering Team, the candidates will work with a team of scientists being a focal point within the wider R&D department.

 

Your key responsibilities will include:

  • Design of gene knock-out, knock-in and strategies using contemporary gene editing technologies (e.g., CRISPR-Cas9).
  • Execution of contemporary gene editing technologies, primarily in human iPSCs – including sample tracking QC and data interpretation.
  • Perform the design, execution and QC of vector cloning strategies, including but not limited to restriction enzyme, Golden Gate, GIBSON assembly.
  • Stay up to date with key aspects of genetic engineering, vector assembly and novel cell line engineering processes.
  • Seek and take responsibility in management of daily and weekly workload/tasks (in conjunction with direct line manager), becoming increasingly independent. Highlight areas of risk and opportunities to improve efficiency and expedient delivery of work tasks or deliverables.
  • Increasingly with experience, become a point of contact of the Gene Engineering and Technology Team for stakeholders.
  • Monitor key areas of day-to-day laboratory activities – ensure the smooth running of the teams’ activities and identify opportunities to improve or areas of risk.

You…

  • Are a good team player with the ability to prioritise, organise and be responsible for your own workload.
  • Have a track record of optimising SOPs/protocols including the experimental design and empirical assessment and troubleshooting of current SOPs and protocols.

Essential for the role:

  • Degree in Biological Sciences or proven practical experience in either (a) molecular biology or (b) gene editing in human ES /iPSCs cells.
  • Demonstrable experience of mammalian cell culture.
  • Good theoretical knowledge and practical experience in (a) PCR, RT-PCR, Western blotting, nucleic acid extraction and molecular cloning, or (b) genome engineering in mammalian cell lines.
  • Demonstrable understanding of genotyping strategies and interpretation of genotyping results.
  • Good theoretical understanding and knowledge of modern gene editing techniques and their applications.
  • Proven ability to communicate research/project outputs, through written or oral communication.
  • Ability to prioritise, organise and be responsible for own workload.
  • Track record of optimising protocols including the experimental design and empirical assessment of alterations to, or troubleshooting of, current SOPs.

… and possibly…

  • Proven record of contributing to research articles and publications.
  • Practical experience of cellular phenotyping through the use of techniques such as FACS, IHC or other.
  • Track record of optimising scientific processes.
  • Experience of introducing automation and or running automated platforms.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Senior Scientists – Technology Development (Gene Editing and Technology Development)

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for Senior Scientists with experience in molecular biology, mammalian tissue culture and cellular engineering to join our Technology Development Team. The role is focussed on developing and managing a programme of research to develop or implement either existing technology or create novel scientific advancements in cellular programming as pertains to the Gene Engineering Technology Development Team and company-wide Objectives and Key Results (OKRs). Reporting to the Head of Department, Gene Engineering and Technology Development team, candidates will work with a team of scientists being a focal point within the wider R&D department.

 

Your key responsibilities will include:

  • Design, develop and manage the implementation of a programme of research to ensure the company is at the forefront of cellular programming.
  • In concert with the Cell Engineering team, incorporate novel cellular engineering and gene editing technologies, processes and applications.
  • Working closely with the Scientific teams, full accountability for developing customised and creative solutions to achieve the companies’ scientific goals, using the latest molecular and cellular biology technologies.
  • Engage and influence external collaborators (and suppliers). Be involved in initiating, developing and driving collaborations which are critical to the achievement of the team and company Objectives and Key Results (OKRs).
  • Influence and impact across the wider scientific and manufacturing teams as pertains to gene engineering and cell line development and will sit on a number of key committees.
  • Be aware of and regularly scan the horison of the current I.P. landscape and business development requirements of the company.
  • Full line management responsibility for all direct reports, motivating and developing them to achieve high levels of performance and productivity. Oversee development and training activities and coach individuals to perform their roles effectively.
  • Actively lead in developing and maintaining the core cultural aspects of the company and deputise for the Head of Department when required.

You…

  • Are a good team player with the ability to prioritise, organise and be responsible for your own workload and that of others.
  • Have a track record of optimising SOPs/protocols including the experimental design and empirical assessment and troubleshooting of current SOPs and protocols.
  • Have a proven track record of project delivery to tight timelines.
  • Have a thirst for knowledge.
  • Have the ability to independently drive your own research and actively contribute to the projects of colleagues.
  • Enjoy tackling research challenges through critical thinking, scientific rigour and inventiveness.

Essential for the role:

  • A PhD in a relevant area of Biological Sciences or equivalent experience and a passion for problem solving.
  • Track record and proven ability to manage multi-disciplinary work tasks and prioritise workload of team.
  • Proven independent working style, technical problem solving, data analysis and generation of novel ideas.
  • Strong practical and theoretical background in editing mammalian cells – experiment QC and project delivery (>4 years of experience).
  • Proven experience and track record in using molecular biology to provide creative solutions to biological questions or technical problems.
  • Demonstrable commitment to developing managerial skills and a track record of training and development.
  • Practical experience and knowledge of cellular assays and cell phenotyping (FACS, IHC, clonogenic, cytotoxicity and viability).
  • Well-rounded and practical experience in molecular assays and molecular biology (qRT-PCR, scRNA seq, ddPCR, cloning, NGS, gene synthesis, cloning).
  • The ability to effectively communicate with collaborators and present to large groups.

… and possibly…

  • Experience in the use and incorporation of automated workflows.
  • Strong practical and theoretical background in hESC and hIPSC culture (>5 years of experience).
  • Good knowledge and experience of performing modern genetic screens.
  • Experience and understanding of introducing novel workflows/processes and development of platforms for reagent delivery.
  • Experienced with next generation sequencing.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Scientists – Technology Development (Gene Editing and Technology Development)

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for Scientists with experience in molecular biology, mammalian tissue culture and cellular engineering to join our Technology Development Team. The role is focussed on supporting a programme of research that will develop and implement either existing technology or create novel scientific advancements in cellular programming as pertains to the Gene Engineering Technology Development Team and company-wide Objectives and Key Results (OKRs). Reporting to a Senior member of the Technology Development team, candidates will work with a team of scientists being a focal point within the wider R&D department.

 

Your key responsibilities will include:

  • Support the design, development and implementation of a programme of research, primarily through reagent design, construction, delivery and empirical assessment.
  • In concert with the Cell Engineering team, incorporate novel cellular engineering and gene editing technologies, processes and applications.
  • Accountable for developing/executing customised and creative solutions to achieve the companies’ scientific goals, using the latest molecular and cellular biology technologies.
  • Engage and influence external collaborators (and suppliers). Be involved in initiating, developing and driving collaborations which are critical to the achievement of the team and company Objectives and Key Results (OKRs).
  • Influence and impact across the wider scientific and manufacturing teams as pertains to gene engineering and cell line development and may sit on a number of key committees.
  • Oversee development and training activities; coach individuals to perform their roles effectively.
  • Actively lead in developing and maintaining the core cultural aspects of the company.

You…

  • Are a good team player with the ability to prioritise, organise and be responsible for your own workload and that of others.
  • Have a track record of optimising SOPs/protocols including the experimental design and empirical assessment and troubleshooting of current SOPs and protocols.
  • Have a proven track record of project delivery.
  • Have a thirst for knowledge.
  • Have the ability to independently drive your own research and actively contribute to the projects of colleagues.

Essential for the role:

  • A PhD in a relevant area of Biological Sciences or equivalent experience and a passion for problem solving.
  • Ability to manage and prioritise own workload.
  • Strong practical and theoretical background in editing mammalian cells – experimental quality control and project delivery (>2 years of experience).
  • Proven experience and track record in executing techniques in molecular assays and molecular biology (qRT-PCR, scRNA seq, ddPCR, cloning, NGS, gene synthesis, cloning).
  • Experience of coaching, training and development.
  • Experience and knowledge of cellular assays and cell phenotyping (FACS, IHC, clonogenic, cytotoxicity and viability).
  • The ability to effectively communicate with collaborators and occasionally present to large groups.

… and possibly…

  • Experience in the use and incorporation of automated workflows.
  • Strong practical and theoretical background in ESC and HiPSC culture (>2 years of experience).
  • Good knowledge and experience of performing modern genetic screens.
  • Experience and understanding of introducing novel workflows/processes and development of platforms for reagent delivery.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Research Assistants – Technology Development (Gene Editing and Technology Development)

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for Research Assistants with experience in molecular biology and mammalian tissue culture to plan, perform and evaluate genome engineering experiments to generate targeted human iPSCs and mammalian cells. Focused on supporting technological development via the implementation of existing and novel gene editing techniques/platforms. This includes project design, execution and delivery. You will also play a key role in the implementation of new technologies and SOPs as pertains to the Gene Engineering Technology Development Team (GETD) and company-wide Objectives and Key Results (OKRs). Reporting to a senior member of the Technology Development Team, the candidates will work with a team of scientists being a focal point within the wider R&D department.

 

Your key responsibilities will include:

  • Design of gene knock-out, knock-in and strategies using contemporary gene editing technologies (e.g., CRISPR-Cas9).
  • Execution of contemporary gene editing technologies, primarily in human iPSCs – including sample tracking QC and data interpretation.
  • Perform the design, execution and QC of vector cloning strategies, including but not limited to restriction enzyme, Golden Gate, GIBSON assembly.
  • Stay up to date with Key aspects of genetic engineering, vector assembly and novel cell line engineering processes.
  • Seek and take responsibility in management of daily and weekly workload/tasks (in conjunction with direct line manager), becoming increasingly independent. Highlight areas of risk and opportunities to improve efficiency and expedient delivery of work tasks or deliverables.
  • Increasingly with experience, become a point of contact of the Gene Engineering and Technology Development Team for stakeholders.
  • Monitor key areas of day-day laboratory activities – ensure the smooth running of the teams’ activities and identify opportunities to improve or areas of risk.

You…

  • Are a good team player with the ability to prioritise, organise and be responsible for your own workload.
  • Have a track record of optimising SOPs/protocols including the experimental design and empirical assessment and troubleshooting of current SOPs and protocols.

Essential for the role:

  • Degree in Biological Sciences or proven practical experience in either (a) molecular biology or (b) gene editing in human ES /iPSCs cells
  • Demonstrable experience of mammalian cell culture.
  • Good theoretical knowledge and practical experience in (a) PCR, RT-PCR, Western blotting, nucleic acid extraction and molecular cloning, or (b) genome engineering in mammalian cell lines.
  • Demonstrable understanding of genotyping strategies and interpretation of genotyping results.
  • Good theoretical understanding and knowledge of modern gene editing techniques and their applications.
  • Proven ability to communicate research/project outputs, through written or oral communication.
  • Ability to prioritise, organise and be responsible for own workload.
  • Track record of optimising protocols including the experimental design and empirical assessment of alterations to, or troubleshooting of, current SOPs.

… and possibly…

  • Proven record of contributing to research articles and publications.
  • Practical experience of cellular phenotyping through the use of techniques such as FACS, IHC or other.
  • Track record of optimising scientific processes.
  • Experience of introducing automation and or running automated platforms.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Technical Assistant – Gene Engineering and Technology Development

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for a Technical Assistant with experience in molecular biology to plan, perform and evaluate vector generation required for targeting Human iPSCs and mammalian cell lines. Focused on supporting the delivery of multiple vectorology projects, help co-ordinate the delivery of vectors and implementation of novel technologies and SOPs as pertains to the Gene Engineering Technology Development Team and company-wide Objectives and Key Results (OKRs). Reporting to a senior member of the Gene Editing Technology Development Team, the candidate will work with a team of scientists being a focal point within the wider R&D department.

 

Your key responsibilities will include:

  • Execution and optimisation of cloning platforms – to include automation and QC reporting.
  • After a period of training – oversee the design, execution and QC of vector cloning strategies, including but not limited to restriction enzyme, Golden Gate, GIBSON assembly.
  • Stay up to date with Key aspects of genetic engineering, vector assembly and novel cell line engineering processes.
  • Seek and take responsibility in management of daily and weekly workload/tasks (in conjunction with direct line manager), becoming increasingly independent. Highlight areas of risk and opportunities to improve efficiency and expedient delivery of work tasks or deliverables.
  • Increasingly with experience, become a point of contact of the Gene Engineering and Technology Team for stakeholders.
  • Monitor key areas of day-day laboratory activities – ensure the smooth running of the teams’ activities and identify opportunities to improve or areas of risk.

You…

  • Are a good team player with the ability to prioritise, organise and take pride in project delivery.
  • Have a track record of optimising SOPs/protocols including the experimental design and empirical assessment and troubleshooting of current SOPs and protocols.

Essential for the role:

  • Degree in Biological Sciences or proven practical experience in either (a) molecular biology, or (b) gene editing in human ES /iPS cells
  • Experience of mammalian cell culture.
  • Good theoretical knowledge and practical experience of either (a) PCR, RT-PCR, Western blotting, nucleic acid extraction and molecular cloning, or (b) genome engineering in mammalian cell lines.
  • Experience of primer design and capillary sequencing.

… and possibly…

  • Track record of optimising scientific processes.
  • Ability to use sequence manipulation software (such as Seq Builder, Snapgene).
  • Experience of introducing automation and or running automated platforms.
  • Good theoretical understanding and knowledge of modern gene editing techniques and their applications.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Senior Marketing Associate

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Cambridge Based Position

 

Your role in our team:

Working within the marketing team as the Senior Marketing Associate, you’ll be at the heart of supporting all marketing activity at bit.bio. An important cog in the marketing wheel, you’ll be expected to be involved at all levels, including campaigns, customer segmentation, and organising conferences and events.

The Senior Marketing Associate will support the work of Marketing Managers and Executives on projects directed at maximising company profits and developing sales strategies such as lead generation or marketing campaigns. You will work closely with employees in other functions such as sales, distribution, science and be expected to work with external stakeholders such as creative agencies.

This job is full of variety and you’ll need to be able to turn your hand to a multitude of tasks.

 

Your key responsibilities will include:

  • Work with the marketing team to create and execute traditional and digital marketing campaigns, aligning them with the overall commercial strategy and tactical plan.
  • Manage the customer/lead data capture process.
  • Undertake various daily administrative tasks to ensure functionality and coordination of the marketing team’s activities.
  • Be the marketing expert for Pardot.
  • Support the marketing team with various projects.
  • Manage content upload and admin tasks for various marketing platforms.
  • Produce and distribute marketing materials and analyse the impact of marketing campaigns.
  • Employ marketing research and analytical techniques to gather important data.
  • Assist database and spreadsheet management including integration of data fields, ensuring data quality.
  • Initiate, organise and execute events, exhibitions, webinars, conferences and seminars.

You…

  • Have a Bachelors’ degree in Marketing, Business or related field.
  • Have industry experience in a marketing role of at least 2 years.
  • Are confident, creative and adaptable.
  • Are able to think and work independently.
  • Are highly organised, reliable and work well within a team.
  • Have a good eye for detail with a high standard of written and verbal communication.
  • Preferably have a scientific background.

Essential for the role:

  • Proven marketing experience gained in a similar role within the Life Science, Biotech or tools & reagents industries.
  • An understanding of the basic requirements of marketing including research, analysis and promotional channels.
  • Excellent computer skills.
  • Highly developed communication skills to be able to work with various levels of people including various stakeholders within the company and outside agencies.

… and possibly…

  • Experienced in the use of design software such as InDesign.
  • Experience and user capability in email platforms.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Senior Product Marketing Specialist / Product Marketing Manager

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Cambridge Based Position

 

Your role in our team:

bit.bio is looking for a Senior Product Marketing Specialist / Product Marketing Manager to join our Products team. We are looking for an enthusiastic and results oriented product marketer who has extensive experience in market development and strategic marketing within the life science, tools and reagents or biotech industry.

 

Your key responsibilities will include:

  • Create and build product messaging that sets new products apart from others in the market to give them a unique selling point.
  • Communicate the vision and value of new products to the market and develop sales and marketing tools that facilitate the selling process.
  • Delivering a range of product focused marketing campaigns and sales enablement material for distributors, external collaborators etc.
  • Create online and offline campaigns, including design/print & production, presentations and the development of various marketing collateral.
  • Deliver marketing literature, including brochures, leaflets and award entries.
  • Creating marketing and social media materials that communicate product features and target key decision makers.
  • Plan and participate in the launch of new services and products which involve several different departments.
  • Obtain insights into customers’ usage of current products, untapped opportunities and buyer personas, through interviews, surveys, focus groups and sales data.
  • Create content such as case studies, videos, digital media (including social media), website copy, blog posts, and copy for public relations.
  • Developing and maintaining the product roadmap. Supporting the product management team during development and launch of new products.
  • Conduct, analyse and present market research to the wider team.
  • Detailed research and analysis of brand / product competitors with an aim to maintain the company’s trusted premium status, improve best practice and boost sales.

You…

  • Have a Bachelors or PhD degree in Biology, Molecular Biology or related field.
  • Have extensive experience leading marketing and strategy.
  • Have excellent writing and editing skills, particularly for communicating scientific information, applications and articles of interest, accurately and appropriately to different target customer segments.
  • Are an outstanding communicator, with the ability to effectively communicate value proposition and technical information to a range of customer and internal audiences.
  • Are able to travel throughout Europe and internationally as required.

Essential for the role:

  • Previous experience of marketing, and or sales, in Life Sciences/Biotech in the tools and reagents areas.
  • Track record of success in product messaging and positioning.
  • Track record of success in launching new, complex products, and achieve excellent business results; developing and implementing marketing and go-to-market/ commercialisation strategies that have consistently met or exceeded planned objectives.
  • Strong strategic planning and analysis skills in sales, marketing and business (competitive) strategy.
  • Experienced in developing and deploying global integrated marketing programs; biotech and/or life sciences industry and related products.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Laboratory Supervisor

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Office Based Position

 

Your role in our team:

We are looking for a Laboratory Supervisor with a strong background laboratory operations and Good Laboratory Practice to oversee all laboratory activities to support Production and Research Scientists in our efforts to provide the best human cells for research and drug discovery. Reporting to our Laboratory Compliance Manager, the candidate is an experienced member of the Operations team who combines supervisory skills with knowledge of safety and Good Laboratory Practice to ensure effective laboratory operations while maintaining high levels of safety, quality and service.

 

Your key responsibilities will include:

  • To supervise and direct a team of Laboratory Support Technicians.
  • To oversee all activities within the laboratory.
  • Ensure all equipment/instrumentation is properly maintained and serviced, complying with regulatory standards to ensure proper performance and functionality.
  • Develop, implement and maintain equipment PPM, service and calibration process.
  • Establish and maintain strong relationships with the laboratory teams to understand their needs and support their workload, challenges and constraints.
  • Implement industry best practice (LEAN, 5S, Kanban) to ensure the laboratory is adequately stocked with consumables, reagent and in-house aliquots in a clearly organised and accessible manner.
  • Monitor work patterns and equipment usage trends.
  • To promote SHE, H&S awareness across the science and laboratory functions; to promote green lab and 3R’s.
  • Identify training gaps, co-ordinate laboratory QEHS and equipment training.
  • Create and report monthly lab metrics.
  • To author and approve SOPs relating to laboratory activities.

You…

  • Have a Bachelors’ degree in a scientific discipline or equivalent experience.
  • Have significant experience working in a cell culture laboratory that includes time spent in a commercial/industry environment.
  • Have proven supervisory experience.
  • Have strong communication skills with the ability to interact with both internal and external stakeholders at all levels.
  • Have strong organisational and time management skills with the ability to prioritise and multi-task.
  • Are proactive and self-motivated. Keen to learn.
  • Are flexible with the ability to adapt to change.
  • Are sincere and secure.
  • Are astute and persuasive.

Essential for the role:

  • Experience of controlled or quality driven environments.
  • Excellent aseptic technique.
  • The scientific knowledge required to analyse lab data and provide support to support to scientists.
  • Knowledge of and practical experience with Kanban.
  • Familiarity with LEAN principles (6 sigma) and 5S.
  • Experience in some form of GxP or familiarity with GMP.

… and possibly…

  • Experience of setting up new processes and continuous improvement.
  • An understanding of the crossover/interface between R&D and manufacturing.
  • Previous line management experience.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Principal Scientist – Cellular Phenotyping

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for a Principal Scientist with a strong background in high content analysis to join our newly formed Cellular Phenotyping team and to support our efforts in cell characterisation and research into methods to derive specific cell types from human pluripotent stem cells. Reporting to our Head of Cellular Phenotyping, you will be accountable for the set up and management of high content devices. You will run your own experiments, give guidance to the wider R&D team for access and troubleshooting and contribute to the development of image and data analysis pipelines.

 

You…

  • Have a PhD or comparable level of education in life science or engineering disciplines.
  • Have experience with cell characterisation with imaging and/or flow.
  • Have demonstrable knowledge of cell imaging.
  • Have an understanding of complex cell culture systems.
  • Have a strong scientific communication record including publications.
  • Have the technical ability to plan, execute and record experiments.
  • Have organisational rigour with an interest in innovating processes.
  • Are an excellent communicator who fosters ‘team-spirit’.
  • Have a passion for scientific impact and a demonstrable independent drive for expanding own scientific knowledge.

Essential for the role:

  • Delivering training in laboratory processes involving cell imaging.
  • Driving scientific projects involving data analysis through to completion.
  • Supervising junior scientists and fostering strong teamwork.

… and possibly…

  • Demonstrable experience of working with human stem cells.
  • Previous involvement in screening campaigns or high throughput applications.
  • An understanding of genomics, gene editing techniques or precision medicine.
  • An expertise, interest or understanding of laboratory automation, microscopy, image data and metadata collection, establishment of workflows and pipelines or programming.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Senior Scientist – Cellular Phenotyping

Location: Babraham Research Campus, Cambridge
Type: Full time, fixed term contract | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for a Senior Scientist with a strong background in high content analysis to join our newly formed Cellular Phenotyping team and to support our efforts in cell characterisation and research into methods to derive specific cell types from human pluripotent stem cells. Reporting to our Head of Cellular Phenotyping, you will run your own experiments and be involved in troubleshooting and development of image and data analysis pipelines.

 

You…

  • Have a PhD or comparable level of education in life science or engineering disciplines.
  • Have experience with cell characterisation with imaging and/or flow.
  • Have demonstrable knowledge of cell imaging.
  • Have an understanding of complex cell culture systems.
  • Have a strong scientific communication record including publications.
  • Have the technical ability to plan, execute and record experiments.
  • Have organisational rigour with an interest in innovating processes.
  • Are an excellent communicator who fosters ‘team-spirit’.
  • Have a passion for scientific impact and a demonstrable independent drive for expanding own scientific knowledge.

Essential for the role:

  • Delivering training in laboratory processes involving cell imaging.
  • Completion of scientific projects involving data analysis.
  • Working as part of a laboratory team.

… and possibly…

  • Demonstrable experience of working with human stem cells.
  • An interest in translational research applications.
  • Experience in a range of techniques with interest in innovation and processes.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Senior Scientist – Pluripotent Stem Cell Platform

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for a Senior Scientist to join our human Pluripotent Stem Cell Platform team. Reporting to the Head of Manufacturing, the successful candidate will work in collaboration with our R&D, Gene Engineering and Manufacturing teams to provide fully validated iPS cells. You will be a key player in executing this workflow within the company, responsible for the design, execution and reporting of experimental work; supervision and training of junior staff; as well as SOP and assay development. This is an opportunity to join one of the best stem cell reprogramming labs and conduct research with a real-world impact.

 

Your key responsibilities will include:

  • Delivery of fully validated iPS cells for the R&D and Product Development teams by overseeing iPS cell culture and quality assessments.
  • Line-managing, advising and coaching junior members in the laboratory by providing intellectual and practical support.
  • Developing, optimising and implementing SOPs for iPSC production and QA / QC assays.
  • Reporting key performance data to the Head of Manufacturing.
  • Promoting a pro-active, continuous development culture within the team.
  • Pro-actively identifying new technologies for the production and assessment of iPSCs.

You…

  • Have a PhD in life sciences (or equivalent experience) with a minimum of 3-years practical lab experience in a relevant industry or scientific organisation.
  • Are a motivated scientist demonstrating the highest scientific rigour, operational skills and work standards.
  • Are a passionate team player with excellent communication skills.
  • Are humble – sincere and secure – accepts own mistakes – prioritises team over personal goals.
  • Are hungry – driven and proactive – goes above and beyond the call of duty to achieve company results.
  • Are smart – astute and persuasive – uses emotional intelligence to lead and inspire colleagues.

Essential for the role:

  • Human iPSC biology, reprogramming, culture and processing.
  • Cell characterisation methods (ICC, qPCR and other assays).
  • Supervisory and/or line-management experience.
  • Staff training experience.

… and possibly…

  • Experience developing and implementing SOPs.
  • Experience in iPSC production or a similar manufacturing environment.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Scientist – Pluripotent Stem Cell Platform

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for a Scientist to join our human Pluripotent Stem Cell Platform team. Reporting to the Senior Scientist, the successful candidate will perform lab work to provide fully validated iPS cells. You will be a key player in executing this workflow within the company, responsible for the execution and reporting of experimental work; supervision and training of junior staff; as well as contributing to SOP and assay development. This is an opportunity to join one of the best stem cell reprogramming labs and conduct research with a real-world impact.

 

Your key responsibilities will include:

  • Supporting the delivery of fully validated iPS cells for the R&D and Product Development teams by performing iPS cell culture and quality assessments.
  • Advising and coaching junior members in the laboratory by providing intellectual and practical support.
  • Developing and optimising SOPs for iPSC production and QA / QC assays.
  • Contributing to a pro-active, continuous development culture within the team.
  • Pro-actively identifying new technologies for the production and assessment of iPSCs.

You…

  • Have a BSc in life sciences with a minimum of 3-years practical lab experience in a relevant industry or scientific organisation.
  • Are a motivated scientist demonstrating the highest scientific rigour, operational skills and work standards.
  • Are a passionate team player with excellent communication skills.
  • Are humble – sincere and secure – accepts own mistakes – prioritisies team over personal goals.
  • Are hungry – driven and proactive – goes above and beyond the call of duty to achieve company results.
  • Are smart – astute and persuasive – uses emotional intelligence to lead and inspire colleagues.

Essential for the role:

  • Human iPSC biology, reprogramming, culture and processing.
  • Cell characterisation methods (ICC, qPCR and other assays).
  • Staff training experience.

… and possibly…

  • Experience developing and implementing SOPs.
  • Experience in iPSC production or a similar manufacturing environment.
  • Supervisory and/or line-management experience.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Senior Scientist – Stem Cell and Neurodevelopmental Biology

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for a Senior Scientist with a solid understanding of the molecular principles underlying the specification of glial lineages, especially astrocytes, and experience with the generation of these cell types from iPSCs. The candidate will work with a team of R&D scientists, manufacturing scientists, commercial teams and external collaborators to support our efforts to develop and validate a range of new human iPSC-derived neurons. The candidate will be expected to lead a project and possibly a team of scientists in driving the project to success.

 

Your key responsibilities will include:

  • Advising, designing and executing reprogramming strategies to obtain pure and well-defined populations of human iPSC-derived glia cells.
  • Supporting collaboration with external partners to develop and characterise new cell types and disease models.
  • Supervising scientists of various grades to deliver R&D programs in a timely manner.
  • Working closely with the project management, product development team and product management to meet new product launch timelines.
  • Supporting the company in drafting and putting together proposals at various stages of the pipeline.

You…

  • Have a PhD in human pluripotent stem cell derived models for neurobiology, and an additional 3 years of experience with iPSC-derived glia cells in an academic or industrial setting.
  • Have experience in supervising and line managing a team of scientists and understanding of how to motivate a high performing team.
  • Are driven by scientific excellence and are a keen experimentalist with strong attention to details and organisational skills.
  • Have hands on experience in collaborative project management.
  • Are a keen team player who will enjoy working at the interface of the wider science team to support the company’s cell type development efforts, with all the multitasking and communication skills that it requires.
  • Enjoy tackling research challenges through critical thinking and inventiveness, demonstrating the highest scientific rigour and work standards.
  • Are comfortable and used to working to tight timelines and managing workload and priorities.

Essential for the role:

  • Broad knowledge about the molecular mechanisms that define cellular identities in the CNS and the use of iPSC-derived glia cells in disease modelling.
  • Supervisory and training experience.
  • Published relevant work in peer-reviewed journals, preferably first or last authorships.
  • Highly skilled in culturing human pluripotent stem cells and iPSC-derived glia cells, preferably astrocytes.
  • Experience in cell characterisation methods (ICC, qPCR and other assays).
  • Project management experience with internal and external stakeholders.

… and possibly…

  • NGS experience (experimental design, library preparation and/or data analysis).
  • Functional characterisation of glia cells.
  • Extensive network in the field of neuroscience to facilitate collaborations with external partners.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Scientist – Computational Biology

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are seeking a highly motivated scientist to join our expanding Bioinformatics team. Reporting to Senior Scientists, you will be joining a highly collaborative team of computational biologists with diverse skill sets who work together to lead decisions and analysis in discovery and characterisation of reprogrammed cell lines. This is an opportunity to join one of the best stem cell reprogramming start-ups and conduct research with a real-world impact.

 

Your key responsibilities will include:

  • Working collaboratively with the wider computational biology team and experimental stem cell scientists under supervision of senior scientists.
  • Contributing to the design and execution of our ambitious research programmes for uncovering core transcriptional programs that define human cell types.
  • Performing computational analyses and reporting of results.
  • Development of tools to facilitate data interpretation by laboratory scientists.

You…

  • Have a PhD in computational biology or a related biological field with a strong bioinformatics component.
  • Enjoy tackling research challenges through critical thinking, scientific rigour and inventiveness.
  • Are detail-oriented with strong organisational skills for tracking data and recording downstream analysis.
  • Enjoy working in a dynamic team environment and are comfortable working to tight timelines and managing workload and priorities.

Essential for the role:

  • Demonstratable experience with analysis of large high-throughput sequencing datasets (esp. bulk RNA-seq and/or single cell RNA-seq).
  • Good knowledge of bioinformatics tools, resources and public databases.
  • Solid biological knowledge and interest, and familiarity with laboratory experimental design.
  • Proficient in R and/or python.
  • Working knowledge of statistical approaches in data science.
  • Ability to clearly communicate requirements for and results of bioinformatics analyses to wet lab biologists.

… and possibly…

  • Experience of working with ChIP-seq, ATAC-seq and/or other genomic technologies.
  • Familiarity with gene regulatory networks, mechanisms of gene expression, developmental biology, and stem cell biology.
  • Experience in the analysis of whole-genome sequencing data.
  • Oxford Nanopore sequence analysis.
  • Experience with cloud computing (preferably AWS; Nextflow a plus).
  • Experience in development of NGS analysis pipelines for large numbers of samples.
  • Familiarity with version control systems for code reproducibility.
  • Experience in the development of tools that help experimental biologists visualise and interrogate data.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Scientist – Stem Cell and Neurodevelopmental Biology

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for Scientists that has a solid understanding of the molecular principles underlying the specification of neuronal and/or glial lineages and experience with the generation of these cell types from iPSCs. Reporting to our CNS lead and Head of Research, the candidate will work with a team of R&D scientists and external collaborators to support our efforts to develop and validate a range of new human iPSC-derived neurons.

 

Your key responsibilities will include:

  • Advising, designing and executing reprogramming strategies to obtain pure and well-defined populations of human iPSC-derived neurons and/or glia cells.
  • Supporting collaboration with external partners to develop and characterise new cell types and disease models.
  • Supervising research assistants to deliver R&D programs in a timely manner.
  • Working closely with the product development team and product management to meet new product launch timelines.
  • Supporting the company in drafting and putting together proposals.

You…

  • Have a PhD in human pluripotent stem cell derived models for neurobiology.
  • Are driven by scientific excellence and are a keen experimentalist with strong attention to details and organisational skills.
  • Have hands on experience in collaborative project management.
  • Are a keen team player who will enjoy working at the interface of the wider science team to support the company’s cell type development efforts, with all the multitasking and communication skills that it requires.
  • Enjoy tackling research challenges through critical thinking and inventiveness, demonstrating the highest scientific rigour and work standards.
  • Are comfortable and used to working to tight timelines and managing workload and priorities.

Essential for the role:

  • Broad knowledge about the molecular mechanisms that define cellular identities in the CNS and the use of iPSC-derived neurons in disease modelling.
  • Published relevant work in peer-reviewed journals.
  • Highly skilled in culturing human pluripotent stem cells and iPSC-derived neurons and/or glia cells.
  • Experience in cell characterisation methods (ICC, qPCR and other assays).
  • Project management experience with internal and external stakeholders.

… and possibly…

  • NGS experience (experimental design, library preparation and/or data analysis).
  • Functional characterisation of neurons and/or glia cells.
  • Extensive network in the field of neuroscience to facilitate collaborations with external partners.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Research Assistant – Cell Biology (Neuroscience)

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

To support the execution of our ambitious research programmes for generating human cell type diversity by cellular reprogramming, we are looking for motivated and skilled assistant scientists to join our growing science team as part of our neuroscience programme. You will become a key player in the delivery of strategic research activities, being involved in the design, execution and reporting of experimental work. This is an opportunity to join one of the best stem cell reprogramming labs and conduct research with a real-world impact.

 

Your key responsibilities will include:

  • Working collaboratively with the wider team under supervision of senior scientists.
  • Design and execution of experiments, analysis and reporting of results.
  • Providing technical and scientific expertise to the R&D team by contributing to protocol development and diffusion.
  • Working with the wider team to create effective organisation of laboratories (equipment, reagents, workflow).

You…

  • Will join bit.bio as a keen team player driven by a passion for scientific discovery and cell biology.
  • Are a motivated experimentalist with scientific rigour and problem-solving attitude.

Essential for the role:

  • A Bachelor or Master’s degree in cell biology, neurobiology, molecular biology or similar, plus at least 1 year of laboratory experience in a R&D team in industry or academic research lab.
  • Practical experience of human pluripotent stem cells derived neuron / glia cell cultures.

… and desired experience…

  • With cell phenotypic characterisation (RT-qPCR, ICC).
  • Genetic modification techniques (transfection, transduction).
  • Functional assays of in vitro cultured neurons (e.g. MEA analysis).

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Financial Accountant

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Office or Remote Based Position

 

Your role in our team:

We are looking for a Financial Accountant to support the increasing financial requirements associated with the continued expansion of the bit.bio Group. As subsidiaries are added there is a need for the consolidation of our financial information and the implementation of inter-company arrangements. Reporting to our Financial Controller, the candidate will have strong practice-based experience to be able to lead our statutory audits, carry out the necessary IFRS work, and look after our tax and treasury functions.

 

Your key responsibilities will include:

  • Consolidation of monthly and annual accounts for the bit.bio Group.
  • Lead interim and annual statutory audits, liaising with external auditors and internal stakeholders, and assisting in preparation of year end accounts.
  • Prepare necessary IRFS papers and information.
  • Prepare information for tax returns (including P11d’s), working with external advisors.
  • Collate information for R&D tax credit submission.
  • Implement intercompany agreements and transfer pricing policies as required.
  • Prepare and submit quarterly VAT returns.
  • Approve month end journals.
  • Approve month end reconciliations.
  • Supervise the finance elements of the payroll process.
  • Manage the company treasury function.
  • Oversee the company’s foreign currency policy.

You…

  • Have a relevant degree and a professional accounting qualification (ACA or ACCA).
  • Have work experience in a top 10 practice.
  • Have an open-minded flexible approach.
  • Have excellent numerical skills with attention to detail.
  • Have an appreciation of the ‘bigger picture’.
  • Are able to communicate at all levels within an organisation.
  • Are a quick relationship builder.
  • Are able to inspire others.

Essential for the role:

  • Group and consolidation accounting.
  • Intercompany arrangements.
  • Preparation of accounts under US GAAP and IFRS.

… and possibly…

  • Audit experience with a biotech company.
  • Audit experience with international subsidiaries.
  • Audit experience with a listed US company / SOX environment.
  • NetSuite ERP systems experience.
  • Production of statutory accounts.
  • Preparation of tax returns.
  • People management – direct reports.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

QA Manager

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Office Based Position

 

Your role in our team:

We are looking for an experienced member of the Quality team to assist the Head of Quality with the development, implementation and maintenance of an integrated Quality Management System (QMS) across bit.bio.

The initial aim of this role is to develop and implement Quality System processes to ensure the Quality, Safety and Efficacy of products, across all stages of the product lifecycle, within the bit.bio product pipeline. The QA Manager will provide quality and compliance support to all departments and drive quality planning and continuous improvement activities to ensure the QMS is fully integrated into the organisation’s operational and business processes.

There is a requirement to be diplomatic, collaborative, customer focused, change agile, comfortable in leading and adapting to changing priorities in a rapidly growing business.

 

Your key responsibilities will include:

  • Develop, implement and maintain Quality System processes and procedures at the Cambridge site including CAPA, risk management, non-conformances, change control and validation to ensure compliance with internal standards and relevant regulatory requirements.
  • Provide leadership and support to document control specialist in the management and control of QMS documents and records to ensure preparation, control, review and approval is performed on a timely basis.
  • Schedule, plan and perform internal audits in accordance with an approved schedule and progress and monitor corrective actions.
  • Schedule, plan and perform due diligence and routine surveillance audits of third party contractors and suppliers to ensure compliance with company and regulatory compliance.
  • Act as principal QA contact, in liaison with relevant departments, in the handling, reporting of quality issues which arise in the manufacture, testing, packaging and supply of materials or product (both internally and through external parties).
  • Develop, implement and maintain an effective system for handling quality complaints and establish effective feedback mechanisms to determine whether the organisation meets customer requirements.
  • Establish relevant KPI’s to monitor and measure the QMS to ensure conformity and to continually improve its effectiveness and provide status reports and updates to Senior Management at Quality Meetings.
  • Provide quality representation at all Quality review meetings at local and site level.
  • Develop, facilitate and maintain a training matrix (detailing training requirements for job roles) and Develop GMP and Quality related training programmes, ensuring training is delivered in accordance with company policy.
  • Host customer audits and participate in regulatory site inspections.
  • Ensure quality goals and objectives are cascaded down through the organisation.
  • Proactively identify and determine current and future resource requirements – both people and systems – lead in the recruitment and establishment of both in a rapidly growing organisation.
  • Support development of personnel by providing relevant training, tools, skills and motivation to provide opportunities for personal improvement and encourage contribution towards continual improvement.

You…

  • Have a degree level or equivalent qualifications in a relevant discipline.
  • Are humble – sincere and secure – accepts own mistakes – prioritises team over personal goals.
  • Are hungry – driven and proactive – goes above and beyond the call of duty to achieve company results.
  • Are smart – astute and persuasive – uses emotional intelligence to lead and inspire colleagues.

Essential for the role:

  • QA Management role within a cGMP environment.
  • Developing and implementing QMS.
  • Good Manufacturing Practice within a Pharmaceutical or related environment.
  • Good documentation Practice and principles of Data Integrity.
  • Performing internal and external audits (IRCA lead auditor).
  • Proficient use of Excel, Word and PowerPoint.
  • Excellent time management, organisation, and communication skills.

… and possibly…

  • Experienced in working in a scientific / cell therapy environment.
  • Experienced in Continual Improvement Tools e.g. LEAN, 5S, Kanban, Kaizen, RCA, VSM.
  • Experience implementing and/or working with eQMS e.g. Trackwise, MasterControl, Q-Pulse.
  • QESH Management System / ISO9001 / PDCA Training.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

QMS Specialist

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Office Based Position

 

Your role in our team:

  • Develop systems and establish procedures for documenting and monitoring processes such as non-conformities, change controls, deviations, Root Cause Analysis, CAPAs, internal and external audits, supplier approval, risk assessments, continuous improvement and signature register.
  • Lead change management such as non-conformities, change controls, deviations and CAPAs.
  • Ensure that the QA documentation and processes are current and in line with the relevant regulatory requirements.
  • Provide review, approval and QA Technical support to key business partners for the management of quality records e.g. risk assessments, continuous improvement, change controls, non-conformities, deviations, CAPAs, supplier approvals and Root Cause Analysis.
  • Implement, monitor and provide appropriate KPIs for the QA processes, escalate any trending observed to senior management.
  • Create, revise and maintain QA standard operating procedures (SOPs) and other documents as required.
  • Act as QA subject matter expert to support business requirements.
  • Ensure the internal audits are up to date with the 12 month plan and any actions are tracked, followed up and closed in a timely manner.
  • Provide direct Quality team support during customer audits and regulatory inspections.
  • Ensure any actions from customer audits and regulatory inspections are tracked, followed up internally and ensure responses are sent out to the customer/or regulatory bodies in a timely manner.
  • Provide direct support for quality related customer complaint investigations and trending activities and ensure responses are sent to the customer in a timely manner.
  • Provide Quality systems and process training across the business.
  • Provide Quality induction for all new employees, including refresher training.
  • Provide direct Quality team support during customer audits and regulatory inspections.
  • Manage the Archiving of business data, both paper based and electronic.
  • Manage the collation of data reporting of the Annual Product Reviews for approval.
  • Write, review and approve Quality Technical Agreements as and when required.

You…

  • Have a degree level or equivalent qualifications in a relevant discipline.
  • Are humble – sincere and secure – accepts own mistakes – prioritises team over personal goals.
  • Are hungry – driven and proactive – goes above and beyond the call of duty to achieve company results.
  • Are smart – astute and persuasive – uses emotional intelligence to assist and collaborate with colleagues.

With essential experience in…

  • Documentation Control within a cGMP environment.
  • Good Manufacturing Practice within a Pharmaceutical or related environment.
  • Good documentation Practice and principles of Data Integrity.
  • Knowledge and expertise in the QMS processes.
  • Proficient use of Excel, Word and PowerPoint.
  • Excellent time management, organisation, and communication skills.

… and possibly…

  • Experienced in working in a scientific / cell therapy environment.
  • Experienced in Continual Improvement Tools e.g. LEAN, 5S, Kanban, Kaizen, RCA, VSM.
  • QESH Management System / ISO9001 / PDCA Training.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio