Join the bit.bio team

Cambridge Start Up of the Year 2018

bit.bio is an award-winning spinout from the University of Cambridge. Our breakthrough technology combines synthetic and stem cell biology for the precise, efficient and consistent reprogramming of human cells used in research, drug discovery, and cell therapy. At bit.bio, we are passionate about engineering human cells that will enable the medicine of the future. To do this we need talented and curious people who want to make an impact on the future of science and therapeutics.

As a team of individuals, we value science, collaboration, openness, curiosity and creativity. We are united by trust and respect for each other.

bit.bio provides a vibrant and dynamic work environment in an exciting, fast-moving time for biology. We work with cutting edge technologies and with our world-leading scientific advisory board. We conduct pioneering work with real-world impact.

We trust our people to make significant contributions early on with opportunities to be involved in projects that are key to the success and growth of our young company. We invest in people, creating opportunities for personal development in an inclusive multi-skilled team with ambitious goals that provide opportunities to learn on the job from each other.

Creativity and open minds are encouraged for everyone to contribute to the success of the company.

To support bit.bio staff and our culture further, we also offer a competitive salary, highly competitive benefits package including pension contribution scheme as well as health and life insurance.

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company, please send your CV and cover letter to careers@bit.bio

 

Scientist – Stem cell and neurodevelopmental biology

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab Based Position

 

Your role in our team:

We are looking for Scientists that has a solid understanding of the molecular principles underlying the specification of neuronal and/or glial lineages and experience with the generation of these cell types from iPSCs. Reporting to our CNS lead and Head of Research, the candidate will work with a team of R&D scientists and external collaborators to support our efforts to develop and validate a range of new human iPSC-derived neurons.

 

Your key responsibilities will include:

  • Advising, designing and executing reprogramming strategies to obtain pure and well-defined populations of human iPSC-derived neurons and/or glia cells.
  • Supporting collaboration with external partners to develop and characterise new cell types and disease models.
  • Supervising research assistants to deliver R&D programs in a timely manner.
  • Working closely with the product development team and product management to meet new product launch timelines.
  • Supporting the company in drafting and putting together proposals.

You…

  • Have a PhD in human pluripotent stem cell derived models for neurobiology.
  • Are driven by scientific excellence and are a keen experimentalist with strong attention to details and organisational skills.
  • Have hands on experience in collaborative project management.
  • Are a keen team player who will enjoy working at the interface of the wider science team to support the company’s cell type development efforts, with all the multitasking and communication skills that it requires.
  • Enjoy tackling research challenges through critical thinking and inventiveness, demonstrating the highest scientific rigour and work standards.
  • Are comfortable and used to working to tight timelines and managing workload and priorities.

Essential for the role:

  • Broad knowledge about the molecular mechanisms that define cellular identities in the CNS and the use of iPSC-derived neurons in disease modelling.
  • Published relevant work in peer-reviewed journals.
  • Highly skilled in culturing human pluripotent stem cells and iPSC-derived neurons and/or glia cells.
  • Experience in cell characterisation methods (ICC, qPCR and other assays).
  • Project management experience with internal and external stakeholders .

… and possibly…

  • NGS experience (experimental design, library preparation and/or data analysis).
  • Functional characterisation of neurons and/or glia cells.
  • Extensive network in the field of neuroscience to facilitate collaborations with external partners.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Project Coordinator

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Office Based Position

 

Your role in our team:

Our growing company is seeking to hire a Project Coordinator who will be in charge of assisting our Project Manager in organising our ongoing projects. This role involves preparing and monitoring project plans and schedules, organising and participating in stakeholder meetings, along with administrative duties, like maintaining project documentation and handling queries and ensuring that project deadlines are met in a timely manner. To succeed in this role, you should have excellent time management and communication skills, as you’ll collaborate with external and internal teams to deliver results on deadlines. There is a requirement to be diplomatic, collaborative, customer focused, change agile and be comfortable adapting to changing priorities in a rapidly growing business.

 

Your key responsibilities will include:

  • Assist and support the project manager.
  • Coordinate project management activities, resources, equipment and information.
  • Organise, attend and participate in meetings where appropriate and distribute minutes to all project team members.
  • Prepare necessary presentation materials for meetings.
  • Document and follow up on important actions and decisions from meetings.
  • Monitor project progress and handle any issues that arise.
  • Track and communicate project risks and opportunities.
  • Undertake project tasks as required.
  • Act as the point of contact and communicate project status to all participants.
  • Ensure project deadlines are met.
  • Create and maintain comprehensive project documentation, plans and reports.
  • Provide administrative support as needed.

You…

  • Have degree level or equivalent qualifications in a relevant discipline.
  • Have 2-3 years of related professional experience.
  • Are humble – sincere and secure – accepts own mistakes – prioritises team over personal goals.
  • Are hungry – driven and proactive – goes above and beyond the call of duty to achieve company results.
  • Are smart – astute and persuasive – uses emotional intelligence to lead and inspire colleagues.

With essential experience in…

  • Working effectively both independently and as part of a team.
  • Working to tight deadlines and remaining calm under pressure.
  • Excellent organisational and time management skills.
  • Excellent verbal, written and presentation skills.

… and possibly…

  • Experience in working in a scientific / cell therapy environment.
  • Proven work experience as a Project Coordinator or similar role.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Manufacturing Development Scientist

Location: Remote or Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Office Based Position

 

Your role in our team:

We are looking for an experienced member of the Manufacturing Development team to work on the process development, scale-up and optimisation of GMP manufacture for a wide range of iPSC-derived cell types. You will work at the interface of R&D, providing technical and scientific expertise whilst devising robust manufacturing processes which will enable the translation of products from proof of principle to sterile manufacture. The Manufacturing Development Scientist will work closely with the R&D, Quality, Logistics and Commercial teams to deliver a quality product to market. As such, there is a requirement to be diplomatic, collaborative, customer focused, change agile, comfortable in leading and adapting to changing priorities in a rapidly growing business.

 

Your key responsibilities will include:

  • Work collaboratively to develop manufacturing processes, SOPs and process transfer into GMP manufacture.
  • Support the delivery of manufacturing development projects by overseeing their planning, execution and analysis of results. Including optimisation of key processes such as cryopreservation, establishment of QC criteria, running functional assays and in the design of experiments.
  • Coaching and mentoring of junior members of the team by providing intellectual and practical support and ensure group training needs are met.
  • Work with the group lead to establish, monitor and report key performance data to the head of manufacturing e.g. production schedules, group capacity, progress against targets and failure rates.
  • Carry out benchmarking of products and work closely with the Product Manager to meet product launch timelines.
  • Promote a proactive, continual improvement culture and systems to maintain high standards of service and good practice.
  • Proactively identify and determine current and future resource requirements – both people and systems – lead in the recruitment and establishment of both in a rapidly growing organisation.

You…

  • Have a degree in biological sciences / stem cell biology (or related field) with a minimum of 2-years experience in a relevant industry or scientific organisation.
  • Are process oriented and experienced in developing, optimising & implementing workflows, protocols, procedures and resources in a quality management environment.
  • Are a motivated scientist demonstrating the highest scientific rigour, operational skill and work standards.
  • Are humble – sincere and secure – accepts own mistakes – prioritises team over personal goals.
  • Are hungry – driven and proactive – goes above and beyond the call of duty to achieve company results.
  • Are smart – astute and persuasive – uses emotional intelligence to lead and inspire colleagues.

With essential experience in…

  • Human induced pluripotent stem cell biology, characterisation and culture systems.
  • Cell phenotyping and functional end point analysis e.g. flow cytometry, qPCR, ICC, MEA analysis.
  • Excellent time management, organisation and communication skills.

… and possibly…

  • Expertise in continuous improvement and its implementation (e.g. LEAN, 5S) and experience of working to a quality management system.
  • Have experience in cell culture automation systems and implementation for cell manufacture.
  • Have knowledge of cGMP processes & regulations applicable to human iPSCs.
  • Developing operational infrastructure.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Manufacturing Development Research Assistant

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Office Based Position

 

Your role in our team:

We are looking for an experienced member of the Manufacturing Development team to support the process development, scale-up and optimisation of GMP manufacture for a wide range of iPSC-derived cell types. You will work at the interface of R&D, providing technical and scientific expertise whilst devising robust manufacturing processes which will enable the translation of products from proof of principle to sterile manufacture. The Manufacturing Development Research Assistant will work closely with the R&D, Quality, Logistics and Commercial teams to help deliver a quality product to market. As such, there is a requirement to be diplomatic, collaborative, customer focused, change agile, comfortable in leading and adapting to changing priorities in a rapidly growing business.

 

Your key responsibilities will include:

  • Work collaboratively under the supervision of senior members of the team to develop manufacturing processes, SOPs and process transfer into GMP manufacture.
  • Support the delivery of manufacturing development projects by helping in their planning, execution and analysis of results. Including optimisation of key processes such as cryopreservation, establishment of QC criteria, running functional assays and in the design of experiments.
  • Assist in the benchmarking of products and support the Product Manager to meet product launch timelines.
  • Promote a proactive, continual improvement culture and systems to maintain high standards of service and good practice.
  • Proactively identify and determine current and future resource requirements – both people and systems – lead in the recruitment and establishment of both in a rapidly growing organisation.

You…

  • Have a degree in biological sciences / stem cell biology (or related field) with a minimum of 1-years experience in a relevant industry or scientific organisation.
  • Are process oriented and experienced in working to SOPs.
  • Are a motivated scientist demonstrating the highest scientific rigour, operational skill and work standards.
  • Are humble – sincere and secure – accepts own mistakes – prioritises team over personal goals.
  • Are hungry – driven and proactive – goes above and beyond the call of duty to achieve company results.
  • Are smart – astute and persuasive – uses emotional intelligence to lead and inspire colleagues.

With essential experience in…

  • Human induced pluripotent stem cell biology, characterisation and culture systems.
  • Cell phenotyping and functional end point analysis e.g. flow cytometry, qPCR, ICC, MEA analysis.
  • Excellent time management, organisation and communication skills.

… and possibly…

  • Expertise in continuous improvement (e.g. LEAN, 5S) and experience of working to a quality management system.
  • Have knowledge of cGMP processes & regulations applicable to human iPSCs.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Business Intelligence & Reporting Lead

Location: Remote or Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w

 

Your role in our team:

bit.bio has set off on a path to revolutionise drug discovery and cell therapy. We aspire to become a machine-learning company and be insights-driven right from the beginning, to support our strong growth trajectory and mission. The Business Intelligence and Reporting Lead position is being created to spearhead the achievement of this goal at an organisational level. In this role, we require someone with a penchant and instinct for insight generation encompassing every aspect of running an ambitious business with an exciting mission, and a deep experience in running Analytics programmes (platforms and operations).

 

Your key responsibilities will include:

  • Creating and operating a Reporting Infrastructure – lead the creation of management dashboards and visualisations on a diverse set of data pertaining to bit.bio business and operations.
  • Creating and operating a Business Intelligence/ Analytics function – setting up early work on insights generation from a wide variety of data of value from internal and external sources, and creating an ambitious roadmap for analytics.
  • Deploying and operating a Data Analytics platform – putting in place state-of-the-art data analytics infrastructure for integrating and analysing data to serve organisational needs for insights.
  • Building a Machine Learning capability and culture – be responsible for building a prediction-based decision-making culture, where we maximise the ability to use data to forecast the future, continuously learning from it; build a technology infrastructure that supports that culture fully.
  • Support Data Strategy development – provide inputs from a Business Intelligence and Reporting perspective on strategic principles, processes, data, tools and other capabilities required to create a robust data strategy for the organisation.
  • Support Data Standards and Policy development – provide inputs on data acquisition, management, retention and governance with a focus on analytics and reporting, to aid standards and policy development.
  • Support Communications development – provide data-driven stories and inputs to organisational communications’ efforts to make them interesting and insightful.

You have…

  • A deep interest in data as a resource, with instinct and passion for supporting missions that are insights-driven.
  • A proactive and collaborative problem-solving approach and a high level of initiative, along with good ability to organise yourself well at work.
  • An ability to construct and articulate insights-driven stories to a variety of audiences.
  • A Bachelors’ degree followed by a minimum of 10 years’ of relevant experience, in industries that are knowledge-driven, and in roles focused on insights’ development.
  • At least 8 years’ of deep experience in Databases, Reporting and Analytics, Data Integration, Analytics Platforms, Cloud, API design, leading teams and managing a variety of stakeholder expectations.

With demonstrable experience of success and knowledge in:

  • A variety of databases – for managing structured, semi-structured and unstructured information.
  • Requirements Analysis in a Reporting and/or Analytics capacity serving a variety of business functions (at least 3 out of Operations, Marketing, Finance, Manufacturing, Sales, Product Management).
  • Handling insights’ needs of a large department or a small-to-medium sized organisation.
  • Implementing end-to-end projects in Data Integration, Reporting, Analytics, Software Platform deployment, including activities of business case development, project and release management, and testing.
  • Analytics strategy and roadmap development.
  • Building effective analytics’ processes and governing them.
  • Deploying and using analytics tools and platforms (such as Qlik, Tableau, SAS, Microstrategy).
  • Cloud environments.
  • Designing and implementing APIs.
  • Working with a variety of stakeholders at all levels and shaping the thinking around creating insights and being insights-driven.
  • Managing multiple requests and priorities in a fast paced environment.
  • Written communication and presentations articulating complex ideas in simplified comprehensible form.

… and preferably

  • A good exposure and understanding of Machine Learning.
  • A Masters degree in a strong quantitative and/or informatics discipline.
  • A good exposure and understanding of Machine Learning.
  • AWS cloud services knowledge and exposure.
  • Designing and building APIs (RESTful, etc.).
  • Exposure to semantic data integration.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Logistics Technician

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Office Based Position

 

Your role in our team:

A person with the skills and experience to ensure the Logistics function is continually positioned for sustainable growth. The aim of this role is to ensure all incoming and outgoing materials management needs are adequately met. The logistics technician is responsible for receiving, processing and storing sensitive biological stock which is then shipped across the world to our internal and external customers/collaborators. There is a requirement to be collaborative, customer focused, comfortable in adapting to changing priorities in a rapidly growing business.

 

Your key responsibilities will include:

  • Receiving stock (Good-in), store the stock prioritising temperature sensitive products.
  • Picking stock for shipments and preparing orders (Good-out).
  • Establish systems to record and assess all materials quality, movement and expenditure.
  • Be involved in all the shipping activities, including interact with couriers and tracking shipments.
  • Promote systems for the packing, shipping and labelling of high value, biologically sensitive materials.
  • Support the lab team in keeping the lab clean and organised.
  • Be involved in stock management procedures.

You…

  • Have a degree level or equivalent qualifications in a relevant discipline. IATA certification would be advantageous.
  • Are humble – sincere and secure – accepts own mistakes – prioritises team over personal goals.
  • Are hungry – driven and proactive – goes above and beyond the call of duty to achieve company results.
  • Are smart – astute and persuasive – uses emotional intelligence to lead and inspire colleagues.

With essential experience in…

  • Working in a Supply Chain or Logistics role.
  • Excellent time management, organisation, and communication skills.

… and possibly …

  • Experienced in working in a scientific / cell therapy environment.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Inventory Coordinator

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Office Based Position

 

Your role in our team:

The initial aim of this role is to ensure all inventory and purchasing management needs are adequately met. The Inventory Coordinator will work collaboratively with the Materials Manager to develop procedures in line with our developing QEHS management systems that ensure all areas of research have access to the materials they need.

There is a requirement to be diplomatic, collaborative, customer focused, change agile, comfortable in leading and adapting to changing priorities in a rapidly growing business.

 

Your key responsibilities will include:

  • Ensure the warehouse and despatch environment meets all regulatory, QEHS policies and procedures such that employees, visitors and the environment are protected from significant risk.
  • Recording and labelling inventory items to be used in the future and maintaining accurate records.
  • Control and maintain inventory levels making monthly inventory reports.
  • Produce data to support pre-stocking strategies, forecast supply & demand to prevent overstock or out of stocks.
  • Updating the inventory stock list when there’s a movement of stock, investigate & correct discrepancies in reported quantity and location of inventory.
  • Managing stock counts and reconcile with the system.
  • Placing purchasing orders with suppliers, and follow up the orders, ensuring the stock are received timely.
  • Gathering products information and updating the data sheet.
  • Lead & deliver accurate stock counts in all locations in line with business requirements.
  • Monitor accuracy of goods in & goods out, identify discrepancies in real time to ensure 100% accuracy.

You…

  • Have degree level or equivalent qualifications in a relevant discipline.
  • Have QESH Management System / ISO9001 / PDCA Training.
  • Are humble – sincere and secure – accepts own mistakes – prioritises team over personal goals.
  • Are hungry – driven and proactive – goes above and beyond the call of duty to achieve company results.
  • Are smart – astute and persuasive – uses emotional intelligence to lead and inspire colleagues.

Requirements:

  • In depth understanding of inventory management principles.
  • Previous experience of working in a Supply Chain or Logistics role.
  • Excellent time management, organisation, and communication skills.

… and possibly …

  • Experienced in working in a scientific / cell therapy environment.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Scientist – Cells of the gastrointestinal system and associated organs

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab-based position

 

Your role in our team:

To support the execution of our ambitious research programmes for generating human cell type diversity by cellular reprogramming, we are looking for a motivated and skilled bench scientist to join our growing science team. You will become a key player in the delivery of strategic research programmes, being involved in the planning of research projects, design, execution, analysis and reporting of experimental work. This is an opportunity to join one of the best stem cell reprogramming labs and conduct research with a real-world impact.

 

Your key responsibilities will include:

  • Working collaboratively within a small team specialized on cells of the gastrointestinal system and associated organs which is led by a principal scientist, by contributing to planning of experiments, execution and analysis of results.
  • Working closely with the wider R&D, tech transfer and project management teams to meet product launch timelines.
  • Participating in project development by presenting your research to internal stakeholders and external partners.
  • Disseminating bit.bio’s vision and research to scientific and lay audiences.

You:

  • Are driven by scientific curiosity and a keen experimentalist with strong attention to detail, focus, self-discipline and a positive can-do attitude.
  • Enjoy tackling research challenges through critical thinking and inventiveness, demonstrating the highest scientific rigour and work standards.
  • Have research experience that will allow you to prioritize, design, perform and report on experimental work independently.
  • Are a strong team player who will enjoy working collaboratively and supportively.
  • Are comfortable and used to working to tight timelines and managing workload and priorities.

Requirements:

  • A PhD in the field of stem cell biology.
  • Practical experience and knowledge on embryonic or tissue stem cell culture and differentiation.
  • Techniques for molecular and functional characterisation of primary cells or in vitro differentiated stem cell-derived cells (e.g. RNA-seq, ATAC-seq, ChIP-seq, RT-qPCR, ICC, flow cytometry and cell type-specific functional assays).
  • Experience with overexpression of transgenes in mammalian systems.

… and possibly …

  • Practical experience with primary cells or in vitro differentiated cells of organs of gastrointestinal tract or digestive system.
  • Practical experience with 3D cell culture and co-culture methods.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Research Assistant – Cells of the gastrointestinal system and associated organs

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab-based position

 

Your role in our team:

To execute our ambitious research programmes for generating all the human cell types in the dish using our unique reprogramming technology we are looking for a highly motivated and experienced assistant scientist to join our growing team. You will become a key player in the delivery of strategic research programmes, be involved in both the design, execution of experiments and reporting of the research results. This is an opportunity to join one of the best stem cell reprogramming labs and conduct research with a real-world impact.

 

Your key responsibilities will include:

  • Working under daily supervision of a principal scientist in a team of 3 on reprogramming of iPSCs to mature specialized cell types of the gastrointestinal system and associated organs.
  • Design and execution of experiments, and analysis and reporting of results within the dedicated team and the wider R&D team.
  • Keeping excellent records of the experiments, data and protocols.
  • Following and learning the scientific literature related to the project, participating in discussions and journal clubs.
  • Working collaboratively with the wider R&D team on the development of core technologies and effective organization of research (equipment, reagents, workflow).

You:

  • Will join bit.bio as a keen team player driven by a passion for scientific discovery.
  • Are a critical thinker with scientific rigour and inventiveness.
  • Have an excellent attention to detail, focus, self-discipline and a positive can-do attitude.
  • Are comfortable working to tight timelines.

Requirements:

  • A BSc degree in cell biology, molecular biology or similar, plus minimum 1 full year of work experience in a rigorous research lab in industry or academia (on top of the lab work and short internships required for the degree).
  • Significant experience with mammalian primary or stem cell cultures and outstanding aseptic technique.
  • Experience with molecular characterization of cells by RT-qPCR, IF and flow cytometry.
  • Experience with basic molecular biology methods such as RNA/DNA extraction, PCR and primer design.
  • Experience with gene overexpression methods in mammalian cells.
  • Permission to work in the UK.

… and possibly …

  • Experience with human pluripotent stem cell culture.
  • Experience with in vitro differentiation of hPSCs or other stem cells.
  • Experience with functional assays related to liver cells.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Scientist – Discovery Programme (Stem Cell/Molecular Biology)

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab-based position

 

Your role in our team:

To support the execution of our ambitious research programmes for generating human cell type diversity by cellular reprogramming, we are looking for motivated and skilled scientists to join our growing science team as part of our Discovery programme. You will become a key player in the delivery of strategic research programmes, being involved in the planning of research projects, design, execution, analysis and reporting of experimental work. This is an opportunity to join one of the best stem cell reprogramming labs and conduct research with a real-world impact.

We are looking for a Scientist with a strong background in Stem Cell Biology and Molecular Biology to support our efforts in improving existing and developing new methods for cellular reprogramming. Reporting to our Lead of Discovery, the candidate will work with a team of scientists being a focal point within the wider R&D department for Discovery sciences.

 

Your key responsibilities will include:

  • Working collaboratively within the Discovery team, providing intellectual and practical support to projects and guidance to junior members.
  • Supporting the delivery of research projects by contributing to their planning, experimental execution and analysis of results.
  • Participating to project development by presenting your research to internal stakeholders and external partners.
  • Disseminating bit.bio’s vision and research to scientific and lay audiences.

You:

  • Are driven by scientific curiosity and a keen experimentalist with strong attention to details and organisational skills.
  • Enjoy tackling research challenges through critical thinking and inventiveness, demonstrating the highest scientific rigour and work standards.
  • Have a practical research experience that will allow you to design, perform and report on experimental work independently.
  • Are a strong team player who will enjoy working collaboratively and supportively.
  • Are comfortable and used to working to tight timelines and managing workload and priorities.

With essential experience in:

  • A PhD in biological sciences with experience in Stem Cell Biology (or equivalent experience).
  • Practical experience of pluripotent stem cell biology and /or molecular biology.
  • Up-to-date techniques for phenotypic and functional characterisation of mammalian cells.

… and possibly …

  • Practical experience with cellular reprogramming.
  • Knowledge of advanced molecular biology techniques and mammalian transgenesis (transfection, transduction).
  • Experience with single cells experiments.

 

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Scientist – Discovery Programme (Stem Cell/Single-Cell Transcriptional Profiling)

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w
Lab-based position

 

Your role in our team:

To support the execution of our ambitious research programmes for generating human cell type diversity by cellular reprogramming, we are looking for motivated and skilled scientists to join our growing science team as part of our Discovery programme. You will become a key player in the delivery of strategic research programmes, being involved in the planning of research projects, design, execution, analysis and reporting of experimental work. This is an opportunity to join one of the best stem cell reprogramming labs and conduct research with a real-world impact.

We are looking for a Scientist with a strong background in Stem Cell Biology and single cell transcriptional profiling to support our efforts in generating data for modelling approaches and improving methods for cellular reprogramming. Reporting to our Lead of Discovery, the candidate will work with a team of scientists and bioinformaticians being a focal point within the wider R&D department for Discovery sciences.

 

Your key responsibilities will include:

  • Working collaboratively within the Discovery team, providing intellectual and practical support to projects and guidance to junior members.
  • Setting up and performing large scale screening projects.
  • Supporting the delivery of research projects by contributing to their planning, experimental execution and analysis of results.
  • Participating to project development by presenting your research to internal stakeholders and external partners.
  • Disseminating bit.bio’s vision and research to scientific and lay audiences.

You:

  • Are driven by scientific curiosity and a keen experimentalist with strong attention to details and organisational skills.
  • Enjoy tackling research challenges through critical thinking and inventiveness, demonstrating the highest scientific rigour and work standards.
  • Have a practical research experience that will allow you to design, perform and report on experimental work independently.
  • Are a strong team player who will enjoy working collaboratively and supportively.
  • Are comfortable and used to working to tight timelines and managing workload and priorities.

With essential experience in:

  • A PhD in biological sciences with experience in Stem Cell Biology (or equivalent experience).
  • Practical experience of pluripotent stem cell biology and/or single cell transcriptional profiling.
  • Experience with setup and analysis of next generation sequencing experiments.

… and possibly …

  • Experience with lab automation.
  • Practical experience with transgenesis and cellular reprogramming.
  • Knowledge of advanced molecular biology techniques and mammalian transgenesis (transfection, transduction).

 

You are welcome to apply

To be part of our dynamic, growing start-up team and shar our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

 

Head of Pluripotent Stem Cell Platform

Location: Babraham Research Campus, Cambridge
Type: Full time, permanent | Start: Immediate
Salary: Competitive | Hours: 40 p/w

Your role in our team:

We are looking for an experienced scientific leader with excellent track record to develop our human pluripotent stem cell platform. Reporting directly to our Chief Scientific Officer, the candidate will lead a team of scientists at a focal point between the R&D and Cell Production departments. The main objectives of the team are: 

  • To provide core scientific and material support to the R&D and Production teams in all activities related to human pluripotent stem cells (sourcing, characterisation, traceability and quality control, inventory management).
  • To lead innovation and strategic collaborations for the continuous development of the pluripotent stem cell core platform to accompany the company growth.

    Your key responsibilities will include:

    • Leading, inspiring and growing a team of dedicated scientists providing a state-of-the-art human pluripotent stem cell facility to support bit.bio’s R&D and cell production capacity.
    • Operationally responsible for the running of the iPSC core facility.
    • Contributing to the development of company strategic programmes by driving innovation for human pluripotent stem cell culture.
    • Working in close collaboration with other Department Heads (Research, Genetic engineering, Production and Product Management, Clinical translation) to meet scientific, new product launch and clinical objectives.
    • Liaise with external bodies, collaborators and customers on any pluripotent stem cell related matters.
    • Engaging with the academic and industry scientific community to promote and diversify the company pluripotent stem cell activities. 

    You:

    • Have a PhD in life sciences with a minimum of 5-years experience as a stem cell/cell line platform leader in a relevant industry or scientific organisation/institution.

    • Have demonstrated experience in growing and leading a high-performing team of scientists.

    • Are process oriented and experienced in developing, optimising & implementing workflows, protocols, procedures and resources in a quality management environment.

    • Are a motivated scientist demonstrating the highest scientific rigour, operational skills and work standards.

    • Are a passionate team player with excellent communication skills.

    With essential experience:

    • Human pluripotent stem cell biology, characterisation and culture systems.
    • Team leadership and project management involving multiple internal and external stakeholders.
    • Working within a quality management environment.
    • Developing operational infrastructure. 

    … and possibly …

    • Have experience in cell culture automation and cell manufacture.
    • Have knowledge of cGMP processes and regulations applicable to human iPSCs.
    • Have worked in large cell bank organisations.


    You are welcome to apply

    To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

     

    Lead Business Analyst

    Location: Remote or Babraham Research Campus, Cambridge
    Type: Full time, permanent | Start: Immediate
    Salary: Competitive | Hours: 40 p/w

    Your role in our team:

    bit.bio is growing rapidly. Our Operations, Science R&D and Commercial teams are having to set themselves up quickly to function in an integrated fashion – as one enterprise. This requires a large degree of automation and integration of core business processes, and new tools that will help accelerate our R&D and production of innovative products. To make this possible, we require a Lead Business Analyst to work closely with our Heads of departments and their nominated representatives to elicit, discover, validate, document, agree and present process automation and application/tool requirements to our IT/Software Engineering teams. The role will participate actively in testing custom-built and pre-packaged software to provide quality assurance, and carries the added responsibility of setting standards and coaching junior business analysts, acting as their functional lead.

      Your key responsibilities will include:

      • Liaising with Heads of our Operations, Science R&D and Commercial teams and their nominated representatives to understand and shape their process automation and application software/tool needs.
      • Creating business process flow diagrams that capture the context for automation to a high standard, turning them into reusable documentation that can be used as references for further projects.
      • Analysing tool and application requirements in detail, gathering detailed requirements and documenting them using prevalent requirements documentation standards (user stories/Behaviour-driven Development).
      • Developing business cases and contributing to creating/detailing project proposal forms with relevant information including risks/mitigation and effort/cost estimates, for Data infrastructure and IT application development/procurement projects.
      • Researching features of third-party applications and off-the-shelf software and software modules (such as ERP) and producing validation reports against stated requirements of internal stakeholders.
      • Guiding science-focused analysts, bioinformaticians and data engineers on optimal and fit-for-purpose ways of capturing requirements for data tool and algorithm development.
      • Developing a robust set of Business Analysis standards and leading their implementation and adoption.
      • Leading the knowledge transfer of Requirements to development teams.
      • Participating in Agile development sprints as acting Product Owner, maintaining user story and feature backlogs and actively collaborating with business/science stakeholders in prioritising user stories and tasks for upcoming sprints.
      • Leading sprint retrospectives and help business/science stakeholders identify improvements to be included in product backlogs and be considered for future sprints.
      • Leading by example in the adoption of Agile methodologies and participating in the set up of tools (such as JIRA) for management of requirements and the project process.
      • Working with testing teams and business stakeholders to provide Quality Assurance, actively contributing to test plans, scripts and product testing cycles.
      • Actively coach and mentor other Business Analysts in all of the above activities, monitor their progress and performance, and support their professional development.

      You will have:

      • A deep interest in Software Engineering, IT Application Management and the discipline of Business Analysis.
      • A passion to guide and coach other business analysts in the team to achieve a high degree of professionalism and quality in their work and output.
      • A proactive problem-solving approach and a high level of initiative, along with good ability to organise yourself well at work.
      • A Bachelors’ degree in Engineering, Computer Science or any other field that comes with a high degree of training in both structured analytical thinking and visual modeling of ideas.
      • An advanced Business Analysis certification from an industry-accredited body.
      • A minimum of eight years of overall experience in IT Business Analysis, and at least three years’ as a Lead Analyst.
      • At least five years of experience in each of the following:
        • Writing user stories and requirements documentation, using the Behaviour-driven Development method.
        • Working in an Agile environment in medium-sized to large companies, participating in sprints as the product owner and leading sprint retrospectives.
        • Product backlog management.
        • Writing business cases – including performing cost and effort estimations and risks/dependencies/issues analyses.
        • Visual modelling of processes (using Visio or a similar tool) and annotating them with information on inputs, outputs, data transformations and roles.
        • Working in a complex data-driven business environment.
        • Working in a Cloud environment for application and data deployment.
        • Working with analysis of core business processes and requirements for third-party Operations’ software, such as Financial and HR applications/ERP modules.
        • Working with a variety of stakeholders at all levels of the organisation.

      With essential experience and knowledge of:

      • Behaviour-driven development.
      • Behaviour-driven development.
      • Software testing/ Validation.
      • Software Engineering.
      • IT Application Management.
      • Agile methodologies and tools.
      • Business Analysis standards.

      … and possibly …

      • Exposure to scientific and research environments.
      • Exposure to scientific and research environments.
      • Exposure to highly regulated environments.
      • Exposure to IP generation from Process Automation and Software Engineering projects.


      You are welcome to apply

      To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

       

      Document Control Specialist

      Location: Babraham Research Campus, Cambridge
      Type: Full time, permanent | Start: Immediate
      Salary: Competitive | Hours: 40 p/w

      Your role in our team:

      We are looking for an experienced member of the Quality team to co-ordinate and manage all document control activities within bit.bio ensuring compliance with the principles of Data Integrity and all internal and relevant regulatory standards. The initial aim of this role is to develop and implement processes for the control and management of the Quality Management System (QMS) documentation and assume responsibility for the issuance, tracking and control of Standard Operating Procedures, Master Batch Records, Test Records, forms, Protocols and Final Reports.

      There is a requirement to be diplomatic, collaborative, customer focused, change agile, comfortable in leading and adapting to changing priorities in a rapidly growing business.

        Your key responsibilities will include:

        • Develop system and establish procedures for identification and numbering of document types.
        • Create standard templates for QMS controlled documentation.
        • Create, revise and maintain company standard operating procedures (SOP’s) and other documents as required.
        • Format, revise, track and issue of controlled documents including SOP’s, protocols and other QMS documents as required.
        • Manage and assist in the review of cGMP controlled documents as necessary.
        • Issuance of batch production records, tracking of master batch records, tracking of all production records and lot number issuance.• Maintain validation files (validation protocols, validation summary reports, engineering change controls).
        • Interface with other departments regarding documentation requirements.
        • Co-ordination and maintenance of quality system databases and logs.
        • Initiate, complete and maintain change control documents.
        • Provide administration support to the Head of Quality and QA Manager.

        You:

        • Have a degree level or equivalent qualifications in a relevant discipline.

        • Are humble – sincere and secure – accepts own mistakes – prioritises team over personal goals.

        • Are hungry – driven and proactive – goes above and beyond the call of duty to achieve company results.

        • Are smart – astute and persuasive – uses emotional intelligence to assist and collaborate with colleagues.

        With essential experience:

        • Documentation Control within a cGMP environment.

        • Good Manufacturing Practice within a Pharmaceutical or related environment.

        • Good documentation Practice and principles of Data Integrity.

        • Proficient use of Excel, Word and PowerPoint.

        • Excellent time management, organisation, and communication skills.

        … and possibly …

        • Experienced in working in a scientific / cell therapy environment.

        • Experienced in Continual Improvement Tools e.g. LEAN, 5S, Kanban, Kaizen, RCA, VSM.

        • QESH Management System / ISO9001 / PDCA Training.


        You are welcome to apply

        To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio