Driving experimental reproducibility and lot-to-lot biological consistency at scale in human iPSC-derived cells enabled by opti-ox technology
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Biologically relevant media unmasks severe mitochondrial dysfunction in a deterministically programmed iPSC-derived model of Huntington’s disease
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A toolbox of human iPSC-derived microglia in different genetic backgrounds and disease models for neurodegeneration drug discovery
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Harnessing CRISPR-Ready ioGlutamatergic Neurons and ioMicroglia as functional genomics tools for drug discovery
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A scalable and well defined human CNS co-culture platform, suitable for studying excitatory/inhibitory neuron imbalances and the discovery of drugs to treat associated diseases
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Exhibitor Tutorial
Challenges, solutions, and progress in applying human iPSC-derived cells to drug discovery
In drug discovery, researchers need reliable, ready-touse human cell models that deliver reproducible results at every stage of the workflow. Join four industry experts as they present data on bit.bio’s deterministically programmed human iPSC-derived ioCells used across key drug discovery stages. Through case studies and real-world applications, you will learn how these cells and the associated protocols support workflows in target identification, assay development, disease modelling, and toxicology.
Key learning points:
- Discover quick and easy generation of gene knockouts and CRISPR screens for target ID and validation in human iPSC-derived neurons and microglia using CRISPR-Ready ioCells
- Learn about assay development in neuroinflammation and demyelinating diseases using neuronal and glial co-cultures
- Explore disease modelling in excitatory neurons with ALS-associated phenotypes using high-throughput MEA
- See data for predicting drug-induced liver injury in toxicology studies with new human iPSC-derived liver models
Agenda
Date
Tuesday, January 28 2025
Time
8:30 AM - 10:00 AM
Location
Room 24B
Attendees
Attendees will leave the session with knowledge of new solutions to generate human-relevant data in vitro to accelerate drug development.
Speakers
Tim Smith, PhD
Associate Director
Sales
bit.bio
Sales
bit.bio
Malika Bsibsi, PhD
Research Leader
Neurosciences
Charles River Laboratories
Neurosciences
Charles River Laboratories
Austin Passaro, PhD
Global Product Manager
MEA Systems
Axion BioSystems
MEA Systems
Axion BioSystems
Cicely Schramm, PhD
Head of Biology
Cell Imaging
Sartorius
Cell Imaging
Sartorius
Session Chair
Farah Patell Socha, PhD VP Products
bit.bio
Farah Patell Socha, PhD VP Products
bit.bio
Discover how ioCells are being applied in real-world applications
